Week 7

Question 1

This enzyme is responsible for the degradation of catecholamines by oxidation of amine groups…

Answer 1

monoamine oxidase (MAO)

Question 2

What neurotransmitter is considered an oligopeptide?

Answer 2

Enkephalin

Question 3

This type of cell is responsible for re-uptaking neurotransmitters once release in the synapse…

Answer 3

astrocytes

Question 4

The rate-limiting step of catecholamine synthesis is called…

Answer 4

tyrosine hydroxylase

Question 5

What is not converted to a neurotransmitter?

Answer 5

Phenylalanine

Question 6

When heme concentration levels rises, it binds to an aporeppresor in order to shut down the heme synthesis pathway. Identify the enzyme that is affected by this repressor?

Answer 6

ALA Synthase

Question 7

In hereditary protoporphyria, what enzyme of heme synthesis is decreased?

Answer 7

Ferrochelatase

Question 8

The following statement about heme metabolism is FALSE…

Answer 8

a porphyrin with symmetric substitution of side chains is classified as a type III porphyrin

Question 9

What substances have color?

Answer 9

uroporphyrin

Question 10

Protoporphyrin IX is….

Answer 10

intermediate in heme synthesis

Question 11

What is/are aspects of the overall regulation of de novo purine nucleotide synthesis?

Answer 11

AMP, GMP, and IMP shift PRPP amido transferase from a small form to a large form

Question 12

What common precursor in the synthesis of purines?

Answer 12

IMP

Question 13

The conversion of nucleoside 5’-monophophates to nucleosides 5’-triphosphates…

Answer 13

Utilizes a relatively specific nucleotide kinase and a relative nonspecific nucleoside diphosphate kinase

Question 14

What enzyme needs to act on nucleotides in order to make these available for DNA synthesis?

Answer 14

ribonucleotide reductase