Week 6 - Pharmacotherapeutics Flashcards

1
Q

What is Pharmacotherapeutics?

A

The therapeutic uses and
effects of drugs

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2
Q

What are the types of therapeutic actions?

A
  • Restorative
  • Chemotherapeutic
  • Substitutive
  • Supportive
  • Curative
  • Palliative
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3
Q

What is Pharmacodynamics?

A
  • The study of the biochemical and physiological effects of
    drugs and the mechanisms of their action in the body
  • Changes cells physiology by interacting with specific
    molecules and chemicals that are normally found within the body
  • Receptor – usually proteins that drugs bind to achieve a
    pharmacological effect
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4
Q

What is the pharmacological effects?

A
  • Agonist
  • Antagonist
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5
Q

What is Agonist?

A

A drug that produces the
same response as the body

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6
Q

What is Antagonist?

A

A drug that prevents the body’s natural response

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7
Q

What is Absorption?

A

Process of drug entering
bloodstream

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8
Q

What is Distribution?

A

Transportation of drug
from site of absorption
to site of action

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9
Q

What is Metabolism?

A

Process of drug being
converted to less active
form

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10
Q

What is Excretion?

A

Process of drug and
metabolites leaving the
body

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11
Q

What are the action of drugs on the body?

A
  1. Onset of action
  2. Peak plasma level
  3. Drug half life
  4. Plateau
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12
Q

What factors affects medication action?

A
  • Gender
  • Developmental factors
  • Diet
  • Cultural, ethic and genetic factors
  • Environment
  • Phycological factors
  • Illness and disease
  • Time of administration
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13
Q

What is therapeutic classes?

A

Medications are classified according to the pathology they are intended to treat

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14
Q

What are the levels of therapeutic classes?

A

1st level - Main anatomical group
2nd level - Therapeutic sub group
3rd level - Pharmacological sub group
4th level - Chemical sub group
5th level - Chemical substance

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15
Q

What is A in therapeutic classes?

A
  • Alimentary tract and metabolism
  • 1st level, anatomical main group
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16
Q

What is A10 in therapeutic classes?

A
  • Drugs used in diabetes
  • 2nd level, therapeutic subgroup
17
Q

What is A10B in therapeutic classes?

A
  • Blood glucose lowering drugs, excluding insulins
  • 3rd level, pharmacological subgroup
18
Q

What is A10BA in therapeutic classes?

A
  • Biguanides
  • 4th level, chemical subgroup
19
Q

What is A10BA02 in therapeutic classes?

A
  • Metformin
  • 5th level, chemical substance
20
Q

What are example of therapeutic class?

A

Bulk stimulants:
- Absorbs water and expand resulting in increased bulk and moisture, encourages normal peristalsis and bowel motility
- E.g. Metamucil
Stool softeners/ lubricants:
- Increase water retention by coating stool surface with a water immiscible layer for lubricant effect
- E.g. Docusate
Chemical stimulants:
- Stimulate peristalsis
- E.g. Bisacody