Week 6 Hyperlipidemia

Question 1

Low intensity dosage of atorvastatin

Answer 1

10 - 20 mg

Question 2

High intensity dosage of rosuvastatin

Answer 2

20 - 40 mg

Question 3

Recommended treatment for individuals <=75 years with ASCVD

Answer 3

High intensity statin

Question 4

Appropriate treatment for 65 year old with LDL of 200

Answer 4

Atorvastatin 40-80 mg daily

Question 5

Appropriate treatment for 55 year old with LDL 100 and 10 year ASCVD risk of 6.0%

Answer 5

Simvastatin 20 mg daily

Question 6

Smallest / Most dense lipoprotein

Answer 6

HDL

Question 7

Level of triglyceride that is required to calculate LDL

Answer 7

<= 400 mg/dl

Question 8

According to ACC/AHA guidelines, recommended for all individuals regardless

Answer 8

Heart healthy lifestyle habits: diet, exercise, smoking cessation

Question 9

Moderate intensity statin is indicated

Answer 9

DM Type 2 and 10 year ASCVD risk is less than 7.5%

Question 10

Appropriate treatment for a 60 year old with DM type 2 and 10 year risk of 6.5%

Answer 10

Moderate intensity statin

Question 11

NYHS class II - IV heart failure recommendation for statin

Answer 11

Not routinely recommended

Question 12

First second line agent to start if statin ineffective at lowering LDL

Answer 12

Ezetimibe

Question 13

Mechanism of action of ezetimibe

Answer 13

Inhibits cholesterol absorption in small intestine

Question 14

Mechanism of action of cholesevelam (a bile acid binding sequestrant)

Answer 14

Increases LDL receptors on hepatocytes, prevents reabsorption and binds bile acids in the GI tract

Question 15

Most effective drugs available for lowering triglycerides

Answer 15

Fibric acid derivatives (fenofibrate is drug of choice)

Question 16

Never use this fibric acid derivative (Fibrate) with a statin due to its potential to increase rhabdomyolysis

Answer 16

gemfibrozil (Lopid)

Question 17

Largest lipoprotein that carries the most triglycerides

Answer 17

Chylomicrons

Question 18

VLDL is converted to this

Answer 18

intermediate-density lipoprotein (IDL)

Question 19

Desirable level of HDL

Answer 19

> = 60 mg/dl for men and women

Question 20

Lipoprotein levels NOT sensitive to fasting

Answer 20

Total cholesterol, HDL

Question 21

Lipoprotein level highly sensitive to fasting / or NOT fasting

Answer 21

Triglycerides

Question 22

Lipoprotein usually measure via a calculation that depends upon fasting (but can be measured directly)

Answer 22

Low density lipoprotein

Question 23

Number of strata ASCVD risk is based upon

Answer 23

5 (Total cholesterol, Systolic BP, Diastolic BP, DM, Smoking status)

Question 24

Major risk factors for ASCVD

Answer 24

Untreated TC >=240, SBP >= 160 or DBP >= 100, or DM, or current smoker

Question 25

AHA recommendation for daily sodium intake

Answer 25

1500 mg daily