Week 6 Flashcards

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1
Q

What are the layers of the V1

A

6 layers
layer 4 subdivided into 4a 4b 4c
4c into 4c (alpha) 4c (better)

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2
Q

Input and output in the 4c layer of the V1

A

Most of input arrives in layer 4c
magnocellular pathway terminates in 4cA
parvocellular pathway terminates in 4cB

K cells terminate in layers 2, 3

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3
Q

What occurs within the V1

A
  • Cortical Magnification
  • Processing attributes and RF properties
    Orientation processing
    Binocular vision
    Motion direction processing
    Enhanced colour processing
  • Receptive Field Classification
  • Columnar organisation
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4
Q

what is orientation selevtivity

A

striking characteristics of cortical cells
any particular cell will respond only only if orientation of edge or line falls somewhere within rather narrow range – about 15 deg to either side of optimal

Cells in layer 4, less orientation selective than those in other layers

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5
Q

oblique effect definition

A

consistent superiority in performance when visual stimuli are horizontal or vertical, as opposed to oblique

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6
Q

what is binocularity in the LGN

A

Once leave layer 4, ocular segregation gives way to binocular integration.
With few exceptions, all cells outside layer 4 are binocularly driven.

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7
Q

How do cortical cells work in their receptive fields

A
  • Large subset of cortical cells respond best to moving contours
  • Typically respond to one direction of motion only
  • RFs vary in size and for any given region of visual field there are multiple sizes represented
  • Some cortical cells register information about colour
  • Double-opponent processing
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8
Q

single cells in V1 receptive fields

A

Elongated RFs with elongates excitatory and inhibitory regions
Respond best to a bar or an edge of correct orientation and size in correct position on retina
Thus selective for orientation, size and position
Display little or no spontaneous discharge

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9
Q

comples cells in V1 receptive structures

A

Have larger RFs which are not so easily described in terms of discrete On- and Off- regions

Because their responses are not simply given by linear summation of sensitivities of subregions, they are described as non-linear

Respond best to rapidly flickering or moving stimuli, have a preferred orientation and size like simple cells, but are not so specific for stimulus position

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10
Q

What are endstopping cells

A

Some cell responses depend not only on contour orientation but contour length as well – also know as end-stopped cells
Extending the bar length beyond this optimal value dramatically reduces cells response
End-stopping found amongst both simple and complex cells

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11
Q

properties of V1

A

columar organisation of a preferred eye
comulnar organisation of preferred stimulus orientation

all cells in each column have similar preferred orientation

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12
Q

what are hypercolumns

A

This combining of adjacent columns to cover a complete range of stimulus orientations and ocular dominance

Each hypercolumn contains neural machinery for analyzing visual

visual information within a local region of the retina

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13
Q

what are colour blobs in V1

A

Cortical slices stained for enzyme Cytochrome Oxidase reveal “blobs” of cells at the centre of ocular dominance columns

Blob cells are specialised for colour (R/G; B/Y)

Cortical colour processing is more complex
It is called “double opponent” processing

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14
Q

what is colour selectivity

A

responded to some colours but not to others

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15
Q

what are preliminary areas in the V1 used for

A

information about all visual sub-modalities (luminance, colour, movement, stereopsis

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16
Q

How do RFs change as you increase in Visual areas

A

The higher up you go, RFs become larger and retinotopic maps become less precise
but RFs become more specific for particular characteristics eg. Expanding/contracting motion patterns

17
Q

what do the cells in the V2 respond to

A

“illusory contours”

18
Q

what is the size fifference between RFs in the V2 compared to the V1

A

2-3x larger in V2 than V1

retinotopic mapping is less precise

19
Q

how is the V2 different to the V1

A

it can find more complex differences than the simple luminance differences within the V1

differences in contrast or texture

20
Q

how much worse is the contrast defined visual acuity than luminance definded acuity

A

2.5x (0.4logMAR)

21
Q

What is the V2 specialised for

A

disparity/texture

22
Q

what is V3 specialised for

A

texture/form

23
Q

What is the V4 specialised in

A

colour

24
Q

What is the V5 specialised in

A

motion

25
Q

What is the two stream model

A

dorsal - where stream
ventral - what stream

26
Q

What undergoes in the ‘where’ stream

A

anaylses motion and depth, include areas V3, MT and MST and courses dorsally

27
Q

What undergoes in the ‘what’ stream

A

analyses spatial form and courses through several ventral areas including V4 and IT

28
Q

how much larger is the ventral stream than the sorsal stream

A

2.5x larger cortical area devoted to it
3.latency up to 2x slower

Extensive reciprocal connections between streams

29
Q

Blindisight

what is blindsight

A

Although V1 is required for conscious perception, one can be “cortically blind” but be able to “see without visual awareness”

patients perform significantly above chance in some discrimination tasks

30
Q

optic ataxia

A

seeing but not being able to move the hand to a specific object by using vision.

due to damage by the parietal lobe

31
Q

where are the ‘where’ pathways

A

parietal lobe

32
Q

where are the ‘what’ pathways

A

temporal lobe

33
Q

neural development of the LGN and cortex

A
  • LGN overall volume doubles from birth to 6 months and then fairly stable
  • all cells in LGN have reached adult size by about 2 years
  • striate cortex volume adult size by 4 months
  • intense synaptogenesis between 28 weeks gestation and 5-8 months then 40% loss of sysnapsis up 11 years when adult-like
34
Q

neural development in the eye

A

Between birth and approx. 7 years of age, poor visual experience drives inaccurate loss of neural connection

this is known as the ‘critical period’ (Daw)

EARLY VISUAL DISRUPTION CAUSES DISRUPTION TO THE DEVELOPING VISUAL CORTEX - CAN LEAD TO AMBLYOPIA

35
Q

what is Amblyopia

A

a developmental anomaly of spatial vision that is associated with the presence of strabismus, anisometropia, or form deprivation early in life

Typically associated with poor acuity monocularly

Leading cause of preventable monocular vision loss in adults 20-70 years of age

36
Q

amblyopia

A

less than 3%
neuro-developmental disorder
If untreated in childhood,
leads to permanent vision loss in adulthood
lifetime risk of bilateral visual impairment rises from 10% to 18%

37
Q

Pathophysiology of amblyopia

A

LGN cells in layers recieving input from amblyopia eye show shrinkage
Visual cortex - most profound effects of ambylopia are found
shift in this pattern so that most cells are monocular, excited by input from the non-amblyopic eye