Week 5 Flashcards
What are the 5 Pās in Lichen Planus
Puritic, Papule, Purple, Polygonal and Plaque (Phlat)
Is Lichen Planus autoimmune?
NO, Immune mediated only (no antibodies/proteins attacked)
What type of hypersensitivity is Lichen Planus?
Type 4
6 types of Lichen Planus
BEER-UP. Bullous, Erythamatous, Erosive, Reticular, Ulcerative and Plaque.
Atrophic is aka erythematous
Lichen Planus
-histologic->DIF finding
Presence of Fibrinogen at BMZ
What type of Lichen Planus would you use a steroid for treatment?
Erosive/Bullous/Ulcerative (those with ulcerations)
What % malignancy rate does Lichen Planus have?
None, only coincident.
Two types of Lupus Erythematosus?
Systemic
Discoid
Difference between SLE and DLE (2)
- SLE has _______
- DLE only affects _______
SLE has antibodies. DLE only affects oral and skin.
Describing the Skin lesions of DLE (2)
- Hypopigmented centers
2. Hyperpigmented Margins
Describing the Oral lesions of DLE (2)
- Ulcers
2. With Striae
What antibody test is MOST suggestive of SLE?
(positive for) Anti Sm antibodies.
Describing the Oral lesions of SLE (2)
- Ulcers
2. With Striae
Describing the Oral lesions of SLE
-Location(4)
- Vermillion border
- Buccal mucosa
- Gingiva
- Palate
What is NOT included in the differential for Red lesions with SLE??
Leukoplakia
SLE
-histologic->DIF findings (5)
- IgG,2. IgM 3. IgA, 4. C3 5. Fibrinogen
Unique treatment option for SLE and the common one.
Unique: AntiMalarials
Normal: Steroids
What do you most need to determine for an infection of Candida?
WHAT IS THE ROOT CAUSE, because it is a commensal organism!
Predisposing Factors (causing) candida (6)
- *Systemic antibiotics
- Steroids
- Dentures
- Dry Mouth
- Diabetics
- Immunosuppressed HIV
Pseudomembranous Candidiasis
-3 People likely to get this type
- Oldies
- Youngens
- Asthmatics (steroid Inhalers)
Pseudomembranous Candidiasis
-Condition of underlying skin when attempted to wipe off
-The skin underneath is Red, ulcerated and/or eroded
Median Rhomboid Glossitis
-Location(s)* 1ā>2
Midline of tongue, THIS OFTEN SPREADS TO THE PALATE, this is called a Kissing LESION.
Treatments for Candidiasis (3)
-One is specifically for the Angular Cheilitis
- Nystatin, 2. Clotrimazole, ***Iodoquinol/Hydrocortisone for Angular Cheilitis
Oral Submucous Fibrosis (OSF)
-affects epithelial layer or C.T.
BOTH muthertruckers!
Oral Submucous Fibrosis
-Is this safe or premalignant?
Premalignant, NOT FREAKING SCLERODERMA
Oral Submucous Fibrosis
-Clinical features (3)
- Trismus, 2. Pain, 3. Pale Mucosa (a white hue)
Oral Submucous Fibrosis
-Histopath (3)
- Hyperkeratosis!
- DENSE Collagen in C.T.
- Chronic inflammation
Oral Submucous Fibrosis
-Treatment (2)
- Steroids (injected)
2. Surgical splitting of the of Fibrous Bands
