Week 5 Flashcards

1
Q

Describe Merkel Cells

A
  • superficial (SA1); slow adapting to continual stimuli
  • highly sensitive to edges and curvature
  • cells wedged along border of the dermis
  • small receptive fields with multiple hotspots
  • moderately low threshold to indentation (30μm)
  • 0-100 Hz (however, most sensitive to 5 Hz)
  • irregular discharge when stimulated
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2
Q

Describe Meissner corpuscles

A
  • superficial (FA1); fast adapting reactive to change stimuli
  • stack of flattened disks in the dermis just below epidermis
  • stroking velocity or motion across skin
  • small receptive fields with multiple
  • ~40% of innervation in the hand
  • low threshold to indentation (6 μm)
  • sensitive to low frequency vibration (most sensitive to 40-50 Hz but range 1-300 Hz)
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3
Q

What do Merkel Cells detect?

A

highly sensitive to edges and curvature

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4
Q

What is the receptive field of a merkel cell?

A

small receptive field with multiple hotspots

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5
Q

What percentage of the hand’s cutaneous mechanoreceptors do the merkel cells make up?

A

~25%

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6
Q

What is the threshold and frequency of merkel cells?

A
  • moderately low threshold: 30 μm
  • frequency 0-100 Hz (most sensitive to 5 Hz)
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7
Q

What do meissner corpuscles detect?

A

stroking velocity or motion across the skin
- important for grip control

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8
Q

What is the receptive field of the Meissner corpuscle like?

A

small receptive fields with multiple hotspots

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9
Q

What percentage of the hand’s cutaneous mechanoreceptors do meissner corpuscles make up?

A

~40% of innervation in the hand

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10
Q

What is the threshold and frequency of meissner corpuscles?

A
  • low threshold to indentation (6 μm)
  • low frequency vibration 1-300 Hz (most sensitive to 40-50 Hz)
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11
Q

What do ruffini endings detect?

A

Skin stretch

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12
Q

What is the receptive field of ruffini endings like?

A

large receptive fields with only one hotspot

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13
Q

What percentage of the hand’s cutaneous mechanoreceptors do ruffini endings make up?

A

~20 % of innervation in the hand

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14
Q

What is the threshold and frequency of ruffini endings?

A
  • high threshold to indentation (300 μm)
  • low frequency: 0.5 -
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15
Q

What type of afferent axon innervates the Merkel, Messiner, Pecinians, and Ruffinis?

A

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16
Q

Describe the cutaneous mechanoreceptors from superficial to deep

A

Meissner, merkel, ruffini, pacinian

17
Q

Describe ruffini endings

A
  • Deep (SA2): slow adapting to continuous stimuli
  • branched fibers inside a cylindrical capsule
  • large receptive fields with only one hotspots
  • ~20% of innervation in the hand
  • low threshold to indentation (300 μm)
  • low frequency: 0.5 - ???
18
Q

Where are merkel cells usually found?

A

at the tips of our fingers

19
Q

Which cutaneous mechanoreceptors are slow adapting? Which are fast adapting?

A

SA = Merkel, Ruffini
FA = Meissner, Pacinain

20
Q

What does it mean if the mechanoreceptor has a low frequency?

A

Do not need to press hard for them to detect stimulus

21
Q

What do Pacinian Corpuscles detect?

A

vibration through an object

22
Q

What is the receptive field of Pacinian corpuscles?

A

large receptive fields with only one hotspot

23
Q

What percentage of the hand’s cutaneous mechanoreceptors do pacinian corpuslces make up?

A

~15% of innervation in the hand

24
Q

What is the threshold and frequency of pacinian corpuscles?

A
  • extremely low threshold (0.08 μm)
  • pick up high frequencies (300-400 Hz) - 200 Hz
25
Q

Describe the Pacinian Corpuscles

A
  • Deep (FA2); fast adapting
  • vibration through an object
  • onion-like capsule located deep in the skin
  • large receptive fields with only one hotspot
  • ~15% of hand innervation
  • extremely low threshold (0.08 μm)
  • pick up high frequencies (300-400 Hz) - 200 Hz
26
Q

When are pacinian corpuscles used in the real world?

A
  • very sensitve to alternating inputs, such as those seen during mechanical vibration
  • high-frquency complex vibrations are elicited in the skin when scanning textures
  • allowing us to distinguish microscopic differences in texture