Week 4 - Weight Loss Medications Flashcards

1
Q

Which weight loss drug(s) are associated with a suicide risk in children, adolescents, and young adults?

A

Naltrexone/Bupropion

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2
Q

What happens if lorcaserin is given with a CYP2D6 substrate?

A

The serum level of the CYP2D6 substrates can be increased. When both drugs are prescribed the CYP2D6 substrate should be given at a lower dose.

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3
Q

Which weight loss drugs are DEA scheduled drugs?

A
  • Lorcaserin
  • Diethylpropion
  • Phentermine
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4
Q

What on-going monitoring is needed with long-term use of phentermine?

A

Assessment of cardiac status

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5
Q

At what BMI level should bariatric surgery be considered?

A

35 or more

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6
Q

Baseline data for Liraglutide

A
  • HbA1c
  • Lipids
  • Renal function
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7
Q

Ongoing monitoring/assessment needs for liraglutide

A
  • s/s cholecystitis
  • pancreatitis
  • depression
  • suicidal thoughts
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8
Q

What baseline data is needed for Lorcaserin?

A

Assessment to rule out valvular disorders and pulmonary hypertension

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9
Q

What are the ongoing monitoring/assessment needs for Locaserin?

A

CBC with differential for s/s of blood dyscrasias

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10
Q

What patient education is needed with Locaserin?

A
  • Do not become pregnant or breastfeed while on this drug
  • DM patients may experience hypoglycemia
  • If taking CYP2D6 drugs, that dose may need to be increased
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11
Q

What baseline data is needed for naltrexone/bupropion?

A
  • Blood glucose
  • Liver function
  • Renal panel
  • Mental status
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12
Q

What patient education is needed for naltrexone/bupropion?

A
  • Will inhibit the effectiveness of opioids
  • Increased risk of suicidal ideation
  • report thoughts or feelings and see provider
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13
Q

What are the ongoing monitoring needs for naltrexone/bupropion?

A

Periodic liver, kidney and blood glucose levels

Signs and symptoms of:
- depression
- anxiety
- panic attacks
- suicidal ideation
- mania

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14
Q

What baseline data is needed for phentermine?

A

Cardiac assessment

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15
Q

What ongoing monitoring is needed for phentermine?

A

Assessment of cardiac status

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16
Q

What is the appropriate method of discontinuing phentermine and/or topiramate?

A

The dose should be tapered off.

17
Q

What is the therapeutic effect of topiramate?

A

Induces as sense of satiety

18
Q

What patient education is needed for Orlistat?

A

Can cause hypothyroidism in patients on levothyroxine
- Should be taken 4 hours apart from levothyroxine

Can reduce absorption of fat soluble vitamins
- Take a multivitamin daily with A, D, E and K
- Take 2 hours before or after orlistat
- Can intensify effects of warfarin