Week 4 (parts 1 and 2) Flashcards
What are the standard lung volumes and capacities
IRV (inspiratory reserve volume) - 2.5L
Vt (Tidal Volume) - 0.5L
ERV (expiratory reserve volume) - 1.5L
RV (residual volume) - 1.5L
IC (inspiratory capacity) (IRV + Vt) - 3L
FRC (functional residual capacity) (ERV + RV) - 3L
VC (Vital capacity) (IRV, Vt +ERV) - 4.5L
TLC (total lung capacity) (IRV, Vt, ERV +RV) - 6L
what is tidal volume (Vt)
volume of air inhaled or exhaled during a single normal breath (men - 500ml, women - 50ml)
What is inspiratory reserve volume
max amount of air that can be inspired on top of a normal tidal inspiration (men - 3000ml, women - 1900ml)
expirartion
what is expiratory reserve volume (ERV)
max amount of air that can be exhaled folloeing a normla tidal
what is minimal volume (MV)
amount of air that would remain if the lungs collapsed (men 30-120ml, women 30-120ml)
what is an obstructive lung disorder
lung surface area increases, VC,IRV and ERV decrease; RV,FRC,RV/TLC increase
what is a restrictive lung disorder
decreases the lung surface area, decreases the VC,RV,FRC,VT,TLC of the affected lung
what is spirometry
- Spirometry is a method of assessing lung function by measuring the volume of air that the patient is able to expel from the lungs after a maximal inspiration and how fast they can expel it
- It is a reliable method of differentiating between obstructive airways disorders e.g. COPD, asthma and restrictive diseases (where the size of the lungs is reduced) e.g. fibrotic lung disease
- Spirometer converts volumes of inspiration and expiration into a single line trace
what are the most common parameters measured in spirometry
- Vital capacity (VC)
- Forced vital capacity (FVC)
- Forced expiratory volume (FEV) at timed intervals of 0.5, 1.0 (FEV1), 2.0, and 3.0 seconds
- Results are usually given in both raw data (litres, litres per second) and percent predicted—the test result as a percent of the “predicted values” for the patients of similar characteristics (height, age, sex, and sometimes race and weight).
what are the reasons spirometry is indicated
- to diagnose or manage asthma
- to detect respiratory disease in patients presenting with symptoms of breathlessness, and to distinguish respiratory from cardiac disease as the cause
- to measure bronchial responsiveness in patients suspected of having asthma
- to diagnose and differentiate between obstructive lung disease and restrictive lung disease
- to follow the natural history of disease in respiratory conditions
- to assess of impairment from occupational asthma
- to conduct pre-operative risk assessment before anaesthesia or cardiothoracic surgery
- to measure response to treatment of conditions which spirometry detects i.e bronchodilators
- to diagnose the vocal cord dysfunction
what are the contraindications of spirometry
Contraindications:
* Forced expiratory manoeuvres may aggravate some medical conditions. Spirometry should not be performed when the patient presents with:
* Haemoptysis of unknown origin
* Pneumothorax
* Unstable cardiovascular status (angina, recent myocardial infarction, etc.)
* Thoracic, abdominal, or cerebral aneurysms
* Cataracts or recent eye surgery
* Recent thoracic or abdominal surgery
* Nausea, vomiting, or acute illness
* Recent or current viral infection
* Undiagnosed hypertension
what is the procedure of spirometry
The basic forced volume vital capacity (FVC) test varies slightly depending on the equipment used, either closed circuit or open circuit
Generally, the patient is asked to take the deepest breath they can, and then exhale into the sensor as hard as possible, for as long as possible, preferably at least 6 seconds. It is sometimes directly followed by a rapid inhalation (inspiration), in particular when assessing possible upper airway obstruction
Sometimes, the test will be preceded by a period of quiet breathing in and out from the sensor (tidal volume), or the rapid breath in (forced inspiratory part) will come before the forced exhalation.
During the test, soft nose clips may be used to prevent air escaping through the nose. Filter mouthpieces may be used to prevent the spread of microorganisms
what are the limitations the spirometry test
- The manoeuvre is highly dependent on patient cooperation and effort, and is normally repeated at least three times to ensure reproducibility
- Due to the patient cooperation required, spirometry can only be used on children old enough to comprehend and follow the instructions given (6 years old or more), and only on patients who are able to understand and follow instructions
- Test is not suitable for patients who are unconscious, heavily sedated, or have limitations that would interfere with vigorous respiratory efforts.
- Many intermittent or mild asthmatics have normal spirometry between acute exacerbations, limiting spirometry’s usefulness as a diagnostic tool. It is more useful as a monitoring tool: a sudden decrease in FEV1 or other spirometry measures can signal worsening control
what is FEV1
the volume of air that the patient is able to exhale in the first second of forced expiration starting from full inspiration
(forced expiratory expiratory volume)
what is forced vital capacity (FVC)
the total volume of air that the patient can forcibly exhale in one breath after full inspiration.
Measured in litres.
FVC is the most basic manoeuvre in spirometry tests
what is FEV1/ FVC
the ratio of FEV1 to FVC expressed as a percentage
FEV1 is 70%-80% of FVC in normal subjects (0.7-0.8)
Excellent measure of airway limitation and allows differentiation obstructive from restrictive disease
Standard diagnostic test for COPD
Moderate airflow obstruction 0.5-0.6 (50-60%)
Severe airflow obstruction 0.3 (30%)
Restrictive disease 1.0
What happens to FEV1 and FV during a restrictive disease
Both FEV1 and FV are reduced (in proportion to each other)
FEV1:FVC ratio is normal or increased (>80%)
What happens to FEV1 and FV during a destructive disease
High intrathoracic pressures generated by forced expiration cause premature closure of the airways with trapping of air in the chest
FEV1 is reduced
FEV1:FVC ratio is reduced (<80%)
whats the difference between an obstructive and restrictive disease
obstructive =reduction in airflow, shortness of breath in exhaling air, the air will remain inside the lung after full expiration, COPD, asthma, Bronchiectasis
Restrictive = a reduction in lung volume, difficulty in taking air inside the lung due to stiffness inside the lung tissue or chest wall cavity, interstitial lung disease, scoliosis, neuromuscular disease, marked obesity
what is vital capacity
- Volume of gas that can be exhaled after a full inspiration
- Represents the 3 volumes under volitional control
- Inspiratory Reserve Volume
- Tidal Volume
- Expiratory Reserve Volume
- Normal 3-6L
- Sometimes reduced in obstructive disorders and always in restrictive disorders
- Also diminished in respiratory muscle weakness
Peak expiratory Flow Rate (PEFR):
what is peak expiratory flow rate
- Highest flow that can be achieved during a forced expiration from a full inspiration