Week 4: Inflammation and wound healing

Question 1

Response of vascular system to cell

injury including infection

Answer 1

Inflammation

Question 2

redness in the site of

inflammation

Answer 2

Rubor

Question 3

swelling at the site of

inflammation

Answer 3

Tumor

Question 4

heat at the site of the

inflammation

Answer 4

Calor

Question 5

pain at the site of inflammation

Answer 5

Dolor

Question 6

loss of
function, development of scab where
there is thickening of tissue, leading to
numbness

Answer 6

Function laesa – Virchow

Question 7

accumulation of fluid in the site of

inflammation

Answer 7

Edema

Question 8

o Rapid onset
o Short duration, only last for a 
few days
o Edema
o Mainly neutrophil

Answer 8

Acute inflammation

Question 9

any disease that
comes on slowly and does not
obvious symptoms at first

Answer 9

Insidious

Question 10

WBC’s involved in chronic inflammation

Answer 10

lymphocytes
(agranulated) and macrophages
(phagocyte), plasma cells from
B-lymphocytes (antibodies)

Question 11

fibrotic scarring,
which may lead to loss of
function

Answer 11

Fibrosis

Question 12

restore the tissue to 
its normal (preinjury) state. The 
injurious stimuli are cleared, as 
well as the mediators and 
inflammatory cells. Injured cells 
are replaced, returning to 
normal function

Answer 12

Resolution

Question 13

after removal of 
cellular debris, any necrotic 
parenchymal cells may be 
replaced by new parenchymal 
cells of the same type. It happens 
if the tissue does not return to 
the normal state

Answer 13

Regeneration

Question 14

o Abscess formation

o Process of pus formation

Answer 14

Suppuration

Question 15

o Acute inflammation did not heal
(not a good response)
o Disease examples are 
tuberculosis (bacteria), 
rheumatoid arthritis, chronic 
inflammation of the lungs

Answer 15

Chronic inflammation

Question 16

Hallmark of chronic inflammation

Answer 16

macrophages,

lymphocytes, plasma cells

Question 17

Inflammatory agents of chronic inflammation

Answer 17

silica dust, wood

splinters, metal

Question 18

➢ Means “new growth”
➢ Neoplasm means “tumor/cancer”
➢ Uncontrollable proliferation or
multiplication of cells

Answer 18

Neoplasia

Question 19

cells grow as a 
compact mass (encapsulated) 
and remain at their site of 
origin to localize the infection, 
can be usually felt

Answer 19

Benign

Question 20

growth of cells is
uncontrolled cells can spread
into surrounding tissue and
spread to distant sites.

Answer 20

Malignant

Question 21

(benign neoplasm of

glandular epithelium)

Answer 21

adenoma

Question 22

(benign

neoplasm of the breast)

Answer 22

Fibroadenoma

Question 23

(benign neoplasm

of smooth muscle)

Answer 23

Leiomyoma

Question 24

Malignant

neoplasm of glandular tissue

Answer 24

Adenocarcinoma

Question 25

Malignant neoplasm of

skeletal muscle

Answer 25

Rhabdomyosarcoma

Question 26

Malignant

neoplasm of smooth muscle

Answer 26

Leiomyosarcoma