Week 4- Healing and repair

Question 1

What are the three processes of healing ?

Answer 1

Haemostasis
Inflammation
Regeneration

Question 2

Describe the regeneration stage

Answer 2

Growth of cells to replace lost structures

Question 3

What is required for a successful regeneration post injury

Answer 3

Stem cells

Intact connective tissue scaffold

Question 4

Describe labile tissue giving an example

Answer 4

Continuously dividing tissue- proliferate through life replacing cells that are destroyed. . Surface epithelia, lining mucosa of secretory ducts of the glands of the body, columnar epithelia of GI tract and uterus, transitional epithelium of urinary tract, cells of bone marrow and haematopoietic tissues

Question 5

Describe stable tissues

Answer 5

Quiescent tissue - low levels of replication but can undergo rapid division in response to stimuli and can reconstruct tissue of origin.
Parenchymal cells of liver, kidneys and pancreas, mesenchymal cells such as fibroblasts and smooth muscle cells, vascular endothelial cells, resting lymphocytes and other white blood cells.

Question 6

Describe permenant tissue

Answer 6

Non dividing tissues - cells have left the cell cycle and can’t undergo mitotic division.neurones, skeletal and cardiac muscle cells. No or only a few stem cells that can be recruited to replace cells.