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Paramedic Drug Week 04 > Week 4 Drugs > Flashcards

Week 4 Drugs Flashcards

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1
Q

Chlorpromazine
(Thorazine)
Class

A

Phenothiazine; anti-psychotic: major tranquilizer

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2
Q

Chlorpromazine
(Thorazine)
Mechanism of Action

A

It is a dopamine antagonist, additionally possessing antiadrenergic, antiserotonergic, anticholinergic, and antihistiminergic properties. Works on a variety of receptors in the CNS, causing sedation and anxiety reduction. Has anti-emetic properties.

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3
Q

Chlorpromazine
(Thorazine)
Indications

A

Acute behavioral emergency, nausea and vomiting.

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4
Q

Chlorpromazine
(Thorazine)
Contraindications

A

Coma, presence of sedatives

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5
Q

Chlorpromazine
(Thorazine)
Adverse Reactions
(Side Effects)

A

amnesia, constipation, extrapyramidal (dystonic) reactions, hypotension, impaired glucose tolerance, memory loss, restlessness, sedation, tardive’s dyskinesia,

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6
Q

Chlorpromazine
(Thorazine)
Drug Interactions

A

Intensifies the actions of other CNS depressants such as tranquilizers, benzodiazepines, narcotics, antihistimines, and barbiturates.

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7
Q

Chlorpromazine
(Thorazine)
Dosage and Administration
Adult

A

Adult: 25-100 mg IM

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8
Q

Chlorpromazine
(Thorazine)
Dosage and Administration
Pediatric

A

Pediatric: 0.5 mg/kg

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9
Q

Chlorpromazine
(Thorazine)
Duration of Acton
Onset

A

Onset: 15-30 minutes

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10
Q

Chlorpromazine
(Thorazine)
Duration of Action
Duration

A

Duration: 4-6 hours

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11
Q

Digoxin
(Lanoxin)
Class

A

Inotropic agent, cardiac glycoside, antiarrhythmic

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12
Q

Digoxin
(Lanoxin)
Mechanism of Action

A

Rapid-acting cardiac glycoside with direct and indirect effects that increase the force of myocardial contraction, increase refractory period of the AV node (slows AV conduction), and increase cardiac output.

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13
Q

Digoxin
(Lanoxin)
Indications

A

CHF, rapid atrial arrhythmias, especially atrial fibrillation/flutter

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14
Q

Digoxin
(Lanoxin)
Contraindications

A

V-fib, digitalis toxicity, hypersensitivity to digoxin

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15
Q

Digoxin
(Lanoxin)
Adverse Reactions
(Side effects)

A

Arrhythmas, blurred yellow or green vision, confusion, headache, nausea, seizures, skin rash and weakness

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16
Q

Digoxin
(Lanoxin)
Drug Interactions
These drugs cause and increase in serum digoxin by 50 to 70%

A

-Amiodarone, verapamil, and quinidine may increase serum digoxin concentrations by 50 – 70%.

17
Q

Digoxin
(Lanoxin)
Dosage and administration:
Adult

A

Loading dose of 0.25-0.50 mg IV

18
Q

Digoxin
(Lanoxin)
Dosage and administration:
Pediatric

A

Rarely used

19
Q

Digoxin
(Lanoxin)
Duration of action:
Onset

A

Onset: 5 – 30 minutes IV

20
Q

Digoxin
(Lanoxin)
Duration of action:
Peak Effect

A

Peak effect: 30 – 120 minutes

21
Q

Digoxin
(Lanoxin)
Duration of action:
Duration

A

Duration: Several days

22
Q

Digoxin
(Lanoxin)
Special Considerations

A

Patients receiving digoxin must be placed on a cardiac monitor. Patients with chronic renal failure are prone to digoxin toxicity. Hypokalemia, hypomagnesaemia, and hypercalcemia potentiate digitalis toxicity.

23
Q

Thiamine

Class

A

Vitamin B1

24
Q

Thiamine

Mechanism of Action

A

Combines with ATP to form thiamine pyrophosphate coenzyme, a necessary component for carbohydrate metabolism. The brain is extremely sensitive to thiamine deficiencies.

25
Q

Thiamine

Indications

A

Coma of unknown origin, delirium tremens, beriberi, Wernicke’s encephalopathy

26
Q

Thiamine

Contraindications

A

No contraindications

27
Q

Thiamine

Adverse Reactions

A

Hypotension from too rapid of an injection or too high of a

dose, anxiety, diaphoresis, nausea, vomiting, allergy (rare).

28
Q

Thiamine

Drug Interactions

A

Give thiamine before glucose under all circumstances.

29
Q

Thiamine

Adult Dose

A

100mg slow IV or IM

30
Q

Thiamine

Pediatric Dose

A

10-25mg slow IV or IM

31
Q

Thiamine
Duration of Action
Onset

A

Rapid

32
Q

Thiamine
Duration of Action
Peak Effect

A

Variable

33
Q

Thiamine
Duration of Action
Duration

A

Depends on degree of deficiency

34
Q

Thiamine

Special Considerations

A

Large IV doses may cause respiratory difficulties.

35
Q

Digoxin
(Lanoxin)
Drug Interactions
These drugs can cause a severe heart block

A

-Concurrent use of digoxin and verapamil may lead to severe heart block.

36
Q

Digoxin
(Lanoxin)
Drug Interactions
These drugs may potentiate cardiac toxicity

A

-Diuretics may potentiate cardiac toxicity.

Paramedic Drug Week 04 (1 decks)

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