Week 4 - Cholesteatoma Flashcards
What is a cholesteatoma?
ME mass described as a cyst or tumour (noncancerous)
- epidermal inclusion cyst formed from stratified squamous epithelium
If cholesteatomas are non-cancerous, what’s the danger?
They can erode ossicles and spread to invade and damage surrounding tissues
What are the 2 classifications of cholesteatomas?
- Acquired (Primary or Secondary)
2. Congenital
What is a congenital cholesteatoma composed of?
Residual embryonic cells trapped in the ME
- squamous epithelial cells that produce keratin
- appears as a white mass medial to normal TM in ME cavity
What is the prognosis of congenital cholesteatoma dependent on?
Intact TM and no other otological issues
What two things can an acquired cholesteatoma develop from?
TM retraction or TM perforation
- allow skin and other debris to enter ME
- usually present with hx of poor ET function and chronic OM
What does the cyst-like pouch of an acquired cholesteatoma consist of?
- Dead and viable squamous epithelial cells
- Keratin shed by viable cells
- Enzymes that erode bone
- Cholesterol crystals
- Bacteria
Describe the two types of acquired cholesteatoma
Primary - TM retraction that accumulates epithelium and debris
Secondary - Result of migration of epithelium and debris through a perforation in the TM
What is otorrhea?
Ear drainage/discharge
T/F: A primary acquired cholesteatoma will always remain attached at the point of origin
False: It can eventually pinch off and continue to grow, forming a true cholesteatoma
What are 2 common sites for an acquired cholesteatoma to originate and which part of the ME do they move into?
Pars flaccida into posterior and anterior epitympanum (superior region of ME)
Posterior pars teens into mesotympanum
What are some of the complications caused by cholesteatomas?
- ME - erosion of ossicles and walls
- Posterior extension into the mastoid
- Superior invasion into brain cavity causing meningitis & abscess
- Medial wall - erosion of bony labyrinth causing sudden vertigo or sudden SNHL
- inferior - complication with facial nerve
What symptoms during a case hx might indicate cholesteatoma?
- fullness or pressure in the ear
- hearing loss
- otorrhea (drainage, possibly malodorous)
- otalgia (pain behind/in ear)
- dizziness or vertigo
- muscle weakness on one side of the face
What might a cholesteatoma show up as during a routine ax?
Audiometry: normal, conductive or mixed HL
Immitance: vary from normal to abnormal
How are cholesteatomas managed (from our perspective)?
Amplification
Aural rehabilitation