Week 4 Flashcards

1
Q

Why is serum creatinine not an ideal test for monitoring rejection after a kidney transplant?

A

Serum creatinine is insensitive for rejection and when changes in it are caused by rejection, it is often a late indicator. Other causes of changes in serum creatinine include dehydration, medication, infection, allergic reaction, etc.

Lecture: 210 Kidney Transplantation

Objective: 4. Explain the limitations of serum creatinine as a monitoring tool for kidney transplant recipients.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

The permanent kidney is formed from what 2 metanephric structures?

A

The ureteric bud and metanephrogenic mesenchyme

Lecture: 218 Pediatric Nephrology

Objective: 1. Describe key points in fetal kidney development and how disturbances in these processes can lead to common causes of chronic kidney disease (CKD) in children.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the 4 most common congenital abnormalities of the kidney and urinary tract?

A

1) Hydronephrosis
2) Renal Cysts
3) Renal Dysplasia
4) Renal Agenesis

Lecture: 218 Pediatric Nephrology

Objective: 1. Describe key points in fetal kidney development and how disturbances in these processes can lead to common causes of chronic kidney disease (CKD) in children.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

A 2 year-old is brought to your pediatric clinic by his patients after they noticed swelling in his legs. Urinalysis reveals a protein:creatinine ratio of 3.5 and blood chemistries reveal hyperlipidemia and a serum albumin of 2.2 mg/dL. What is the most likely diagnosis?

A

This is a textbook case of Nephrotic Syndrome. 80% of nephrotic syndrome in patients under the age of 6 is due to Minimal Change Disease.

Lecture: 218 Pediatric Nephrology

Objective: 4. Form a differential/be able to perform initial investigation of common kidney-related pediatric complaints (hematuria, proteinuria, UTI).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly