Week 4, 8 and 10 - Health Economics Flashcards

1
Q

Explain the economic burden of disease

A

Healthcare cost is ↑ due to living longer (past 60 years)
= experience more diseases / complications = expensive to treat
Elderly become more expensive due to issues like HF, cancer etc.
- prescription medicine frequency increases with age

People expect to receive treatment + healthcare professionals may give treatment out of fear of being sued

  • Undiagnosed, untreated hypertension is a WORLD wide problem
  • Burden of CVD is ↑
    - CVD is a leading cause of death
    - expensive due to healthcare cost, indirect cost from premature mortality, indirect costs from premature morbidity
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2
Q

What is the true cost of health and healthcare (esp. in hypertension)

A
  1. Diagnose patient and give them lifestyle advice + medication to reduce high BP (= primary prevention of strokes etc.)
    - primary care / prevention; with nurse, doctor, pharmacist
  2. If already had a CV event, give patient secondary prevention treatment (prevents another event from occurring)
    - secondary care / prevention; with A&E, stroke unit
  3. Due to CV event may have to take time off work, travel to get medication etc.
    - travelling could be a barrier
    - lifestyle changes e.g. going gym = expensive + costs are by patient not inc. in healthcare system
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3
Q

What is intangible cost

A

Is suffering associated with the disease
- can’t add monetary value to it

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4
Q

What are Indirect Costs

A

How society is affected + productivity is lost
- i.e. due to sickness your job loses out on a valuable worker = productivity declines
- may not be able to attend school due to sickness = education is missed
- if die pre-maturely = society has lost out

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5
Q

What are Direct Costs

A

Direct Medical Costs
- costs imposed on healthcare system due to hypertension and CVD
- e.g. primary care, in-patient stroke unit, MI, surgery, rehabilitation
- CAN be FIXED, SEMI-FIXED and VARIABLE costs
- Fixed = “fixed set up cost” = building hospital, “fixed running cost” = lights, water
- Variable = ↑ with more patients you have e.g. medication, food
- Semi-fixed = temp. employment (only employed when it gets busy)

Direct Non-medical Costs
- is patient out of pocket costs e.g. gym membership, childcare

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6
Q

Explain methodological approaches to measure outcome and cost-effectiveness analysis of alternative treatments

A

Ways to reduce cost
- reduce costly CV events e.g. stroke, heart attack
- early diagnosis via BP monitoring
- screen for hypertension

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7
Q

What is intangible cost

A

Is suffering associated with the disease
- can’t add monetary value to it

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8
Q

What are the 4 basic methods of economic evaluation

A

OVERALL: want drug with ↑ effect, ↑ QALY and ↓ cost

  1. Cost Effective Analysis (CEA)
    - used when 2 methods / drugs have diff. effectiveness
    - think about cost of drug + its effectiveness
    - want drug to be in SE quadrant (increased effect + decreased cost)
  2. Cost Utility Analysis (CUA)
    - a type of CEA, using utility methods
    - compare results of diff. diseases + there clinical outcomes
    - outcome is reported as QALYs (= utility value)
  3. Cost Benefit Analysis (CBA)
    - uses willingness to pay / monetary
  4. Cost Minimisation Analysis (CMA)
    - used if 2 methods have the same outcome but want to know what is cheapest
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9
Q

What is Incremental Cost Effectiveness Ratio (ICER)

A

CEA: Diff. in cost (of both drugs) ÷ Diff. in outcome (of both drugs)

CUA: Diff. in cost (of both drug) ÷ Diff. in QALY (of both drugs
- lifetime QUALYs help workout how many life years your buying (e.g. if prevent stroke patients life expectancy isn’t reduced)
- ins similar drugs (similar outcome) QUALY diff. is low

EQUATION:
difference in costs (of all drugs) ÷ difference in outcome

when picking qhich drug tp use may ask “what is the cost required to gain one more QALY”

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10
Q

What is the cost-effectiveness plane

A

x axis = effect (decreased effect to increased effect)
y axis = cost (decreased cost up to increased cost)

Has 4 quandrants:
NE = increased cost and increased effect
NW = increased cost and decreased effect
SE = decreased cost and increased effect
SW = decreased cost and decreased effect

WANT a drug in SE quandrant
DO NOT WANT drug in NW quandrant

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11
Q

How does scarcity and choice influence decisions about health

A

Need to justify why money was spent on one option and not the other

  • resources in healthcare are scarce (not unlimited) = need to choose how we use them + what we use
  • make choices by thinking about benefits + opportunity costs
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12
Q

How does benefits and opportunity costs influence decisions

A

Pick the treatment / intervention that has the highest benefit
- do NOT want to choose treatment where the opportunity cost is higher than the benefit

Opportunity cost = the benefit we are not getting / miss out on

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13
Q

What are the 4 ways outcomes are measured

A

Outcomes refer to the effect on patients

  1. Clinical indicators
  2. QoL (quality of life)
  3. Utility (QALY)
  4. Willingness to pay
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14
Q

How does ‘clinical indicators’ measure outcomes

A

They are specific indicators for a disease
- e.g. hypertension check BP
- e.g. angina check symptoms i.e. severity, duration
- e.g. hyperlipidaemia check HDL, LDL and total cholesterol

Clinical indicators help identify disease + its severity and decide treatment plan
We do NOT measure side effects

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15
Q

How does ‘QoL’ measure outcomes

A

QoL - an subjective evaluation about an individuals life
- affected by physical health, psychological state, personal beliefs, relationships and their environment
- has many domains + sub-divisions (e.g. HRQoL)

2 Types of QoL Measure:
1. Disease specific
- designed to look at QoL for a specific disease
- ADV: can focus on domain considered most important for that disease
- DISADV: harder to compare results between diff. illness + may not include all domains considered important
- e.g. SAQ-7 (angina questionnaire)

  1. Generic
    - UTILITY

PROM - patient reported outcome measure

Physical + mental health influences QoL + well-being
Many medicines improve quality NOT quantity of life

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16
Q

How does ‘UTILITY’ measure outcomes

A

UTILITY is generic QoL measure

  • Attach a value to specific health state (e.g. when healthy + when ill)
  • Difference in value of both states = UTILITY
    - if get treatment = health state improves = gain utility
    - i.e. value goes form low to high
  • Use EQ-5D to measure utility (5 dimensions + 3 level per dimension = 245 possible health states)
    - questionnaire tick what applies / relates to you
  • UTILITY score of 1 (health state 11111) = perfect health
    - 1 = perfect health
    - if have score for a year = 1 QALY
  • If UTILITY score is 0.85 = 0.85 QALY

Can be used to compare outcomes in diff. patients
QALY (quality adjusted life year) - used to quantify UTILITY
- range is 0-1
- without intervention have shorter QALY / patient death

17
Q

How does ‘willingness to pay’ measure outcomes

A