Week 3 - Lab on reflexes Flashcards

1
Q

What are the alpha motor neurones that innervate a muscle referred to as?

A

A muscle’s motorneurone pool

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2
Q

Where do the cell bodies of motor neurones of the limbs and axial skeleton lie?

A

In the ventral horn of the spinal cord

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3
Q

What is a motor unit made up of?

A

The motorneurone and the group of muscle fibres it is connected to

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4
Q

From which pathways for motor neurons receive synaptic input?

A
  • Descending pathways from higher centres involved in voluntary movement and postural control
  • Sensory neurones whose receptive endings lie in muscles, tendons, skin and joints
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5
Q

Why do all muscles of a motor unit discharge together?

A

The excitatory synapse between a motor neurone and each muscle fibre is an extremely secure and efficient one, which means each presynaptic action potential that arrives at the motor endplate ultimately gives rise to a postsynaptic myscle action potential

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6
Q

How are the size of the motor unit action potential, force generated and size of motor units connected?

A

The bigger the motor unit, the larger the motor unit action potential and the force generated

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7
Q

How does the body ensure smaller motor units are used for smaller forces?

A

As strength of excitation of the motorneurone pool is increased, small motor units are fired off first. For stronger excitation, more and larger motor units are recruited into the active population
Order of recruitment is fixed

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8
Q

WHat is a tendon reflex/myotatic?

A

Tapping on the knee reflex
- tap imparts a stretch on the muscle. That change in length is sensed by the muscle spindle sensory neurone, causing a reflex excitation of the motorneurones, opposing the stretch by active contraction of the muscle

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9
Q

How does the tendon reflex help to automatically maintain posture?

A

Automatically regulates muscle length in large postural muscles

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10
Q

How is the inverse myotatic reflex different to the myotatic reflex?

A

Occurs in response to large rises in muscle tension, not length per se
AND
Sensory neurone is located in muscle tendon, not muscle itself
AND
Causes reflex inhibition of motorneurones –> sudden relaxation of muscles

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11
Q

Describe the well known crossed extensor reflex

A

Mediates limb withdrawal from a painful stimulus, while through reciprocal excitatory and inhibitory connections to the motorneurones pool on the opposite side of the spinal cord, it results in automatic extension of the other limb

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12
Q

What can cause hypoflexia?

A

Damage to dorsal or ventral roots, or degradation of afferent or motorneuones
This will also cause a reduction in muscle tone and resistance to stretch

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13
Q

WHat is muscle tone?

A

The continuous and passive partial contraction of the muscles, or the muscle’s resistance to passive stretch during resting state

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14
Q

What could lesions to descending neural pathways cause?

A
  • Descending neural pathways exert effects either on the alpha motorneurones, or on the small gamma motorneurones that act to regulate sensitivity of the muscle spindles
  • Therefore, lesions in descending neural pathways can lead to either hyperreflexia or hyporeflexia, and also to changes in muscle tone and resistance to stretch
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15
Q

What are the electrical events as a subject voluntarily contacts their muscle?

A

Voluntary recruitment means muscle force is modulated by the CNS - combines recruitment with the frequency of MU activation and synchronization

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16
Q

How do electrical events vary as muscle force is increased?

A

As muscle force is increased, a greater number of greater sized muscle units are recruited, increasing frequency of electrical events as more MU fire simultaneously.
– Results in greater voltage generated

17
Q

How can shocks to a nerve evoke movement + sensation?

A

The nerve can be mixed sensory and motor

18
Q

Where is sensation felt when a nerve is stimulated?

A

Can be both at stimulation point and at the endings of the nerve, as stimulation evokes an AP, which can travel down the length of the nerve fibre, and hit the end of a sensory nerve - where sensation is felt

19
Q

What is the motor nerve conduction velocity in healthy peripheral nerves?

A

Should exceed 45ms-1

20
Q

What are some pathological conditions in which motor nerve conduction velocity would be slowed?

A

Multiple sclerosis

Motor neuron disease

21
Q

What can cause a marked augmentation of the patellar reflex response?

A

Asking a patient to grit their teeth and clasp their hands in front of their chest while simultaneously trying to pull their hands apart

22
Q

What is the Babinski sign and what is it caused by?

A

An abnormal plantar reflex consisting of dorsiflexion of the great toe, and fanning of the small toes
This is a result of lesions in the pyramidal tract

23
Q

At what position would you test someone’s bicep muscle strength in a clinical situation?

A

Arm at 90 degrees