week 3 - female reproductive organs Flashcards

1
Q

what is an ovipositor?

A

tube used for laying eggs, but can be more complex than that, in some parasitioid wasps they also contain venom

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2
Q

do only invertebrates have ovipositors?

A

there are some vertebrates that have ovipositors such as japanese bitterling fish where it is inserted into a mussel or the syngnathidae family of sea horses and pipe fish where it is used to insert into the male brood piuch

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3
Q

The main body of the female reproductive anatomy is the ___

A

uterus (corpus body – fundus outside)

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4
Q

from the uterus is the oviduct which has 2 parts known as the?

A

Isthmus and Ampulla

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5
Q

the sperm is capacitated in which part of the female reproductive system?

A

isthmus

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6
Q

fertilisation of the oocyte takes place in which part of the female reproductive system?

A

ampulla

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7
Q

what are the 2 different layers of the uterus?

A

endometrium - inner glandular layer

myometrium - outer muscular layer

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8
Q

the cervix is also known as the?

A

Os

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9
Q

what is the difference between the two parts of the os and how is this different for ejaculation?

A

external and internal os
external os is where primates deposit sperm
internal os is where boars deposit sperm hence the corkscrew shaped penis of the sperm

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10
Q

what are the 4 basic designs of eutherian uterine?

A

duplex
bipartite
bicornate
simplex

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11
Q

explain the duplex uterus

A

2 uteri and 2 cervixes
rodentia and lagomorpha
highly prolific as pregnant on both sides

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12
Q

explain the bipartite uterus

A

2 uteri and one cervix

carnivora and cetacea

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13
Q

explain bicornate uterus

A

2 uterine horns (fused at front but not at the back) and 1 cervix
insectivores and ungulates

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14
Q

explain simplex uterus

A

1 uterus and 1 cervix

primates, chiroptera, edentates

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15
Q

the oocytes come from the ___ -__, these develop in the ___ ___ and estradiol is produced in the first half

A

primordial follicle

secondary follicle

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16
Q

the cells which make up the follicle are destined to become a new structure ___ ___ in the second half of the cycle and produce ___

A

corpus luteum

progesterone

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17
Q

the primordial follicle consists of ____ and ____ cells only

A

oocyte

granulosa

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18
Q

the pre-antral follicle consists of ____, ____, and ___ cells

A

oocyte
granulosa
theca

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19
Q

the antral cells have many layers of?

A

granulosa cells

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20
Q

Estradiol exerts what sort of feedback within the HPG axis?

A

negative feedback

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21
Q

Estradiol acts on endometrial cells as a _____, stimulates proliferation of _____ ready for embryo implantation.

A

mitogen

endometrium

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22
Q

what is luteinization?

A

mixing of vascularised granulosa and theca derived luteal cells

23
Q

progesterone exerts _____ feedback within the HPG axis and thickens ___ ____.

A

negative

cervical mucus

24
Q

Progesterone exerts ____ - _____ effect on the endometrium

A

anti - proliferative

25
Progesterone stimulates differentiation of endometrial cells - known as _____
decidualisation
26
Progesterone also increases ___ ____
blood flow
27
Regression of the corpus luteum is a 2 step process?
functional luteolysis | structural luteolysis
28
what causes regression of the corpus luteum?
decline in LH support | may reflect antigonadotrophic actions of PGF 2alpha
29
the menstrual cycle has 2 phases and what is the length of these?
proliferative phase - 1-14 days | secretory phase - 14-28 days
30
the ovarian cycle is different to the menstrual cycle and starts when?
the peak in estradiol, at day 14 roughly, this then causes a peak in LH and progesterone
31
there are 2 stages to the ovarian cycle
follicular phase | luteal phase
32
what is oestrous?
period of receptivity
33
when should oestrous occur?
at time of menstruation / fertility
34
primordial and pre-antral follicles are ___ ____
gonadotrophin independent
35
early antral follicles respond to ___
FSH
36
late antral follicles respond to ____ and ____
FSH (granulosa) and LH (theca)
37
ovulatory follicles respond to ___
LH
38
what is follicular atresia?
all follicles will die by atresia, the one that doesnt is the oen that ovulates
39
The follicle which doesnt undergo atresia is the dominant follicle, it is the most ____ responsive follicle and makes the most E2. negative feedback from E2 supresses FSH. E2 upregulates LHCGR on GCs
FSH
40
in the follicular phase of the ovarian cycle what is produced?
estradiol - E2
41
in the luteal phase of the ovarian cycle what is produced?
progesterone
42
Meiosis in the female is intiatied in ____ and then arrested
utero
43
after menarche cohorts of oocytes recruited to develop each month until _____
menopause
44
In the first meiotic arrest there is an LH surge in _____, in the second meiotic arrest there is sperm fusion in _____
prophase I | metaphase II
45
the second meiotic spindle is stabilised by ____
MPF - maturation promoting factor
46
the MPF is a complex of what?
cyclin B | cdk1
47
the MPF is stabilised by what?
CSF cytostatic factor
48
Prior to ovulation, oocyte undergoes both ____ and ____ maturation
cytoplasm | nuclear
49
Prior to ovulatory LH surge, there is primary oocyte arrested at ___
prophase I
50
LH surge stimulates resumption of meiosis; oocyte complete meiosis I, ejects first polar body and then arrests again at ___
metaphase II
51
In dogs, prior to ovulatory LH surge, the primary oocyte is arrested at prophase I. The LH surge stimulates ____ without resumption of meiosis. Oocyte resumes meiosis ____ post ovulation
ovulation | 48-54hrs
52
Reflex ovulation or induced ovulation is a ___ trait in eutheria and persists in shrews, rabbits and cats. It is triggered by what?
primitive | mechanical stimulation of the cervix and reproductive tract
53
reflex ovulation is a neural reflex to ______, stimulates ___ ____ which impinge on GnRH neurones. Increase in GnRH pulse amplitude or frequency triggers ____
hypothalamic POA Kisspeptin neurones LH surge
54
Spontaneous ovulation occurs how?
endocrine feedback from ovaries stimulates a spontaneous preovulatory LH surge in the late follicular phase. The LH surge and ovulation occur irrespective of mating