Week 3 Diabetes Flashcards
How does T1D work?
How does T2D work?
T1D facts
- More common in younger people
- S/S normally more abrupt
- NO endogenous insulin production -> must have insulin replacement
- 3 Ps most common: polyphagia, polydipsia, polyuria
T2D Facts
- More common in adults (w/ risk factors)
- Can go undiagnosed for years
- Drs just screen for risk factors, not s/s
- Pts are INSULIN RESISTANT —> treat w/ oral/SQ meds, may need insulin replacement
Symptoms of T2D
Fatigue, recurrent infections (decreased immune system), slow wound healing
What are the 3 Ps associated with T1DM?
Polydipsia, polyuria, polyphagia
Non-modifiable risk factors for T2D
- Family hx of diabetes
- > 45 years old
- Race/Ethnicity
- Hx of gestational diabetes
Modifiable risk factors for T2D
- Physical inactivity
- High body fat or body weight
- High BP
- High cholesterol
Labs involved in diabetes:
Fasting
Casual
Urine ketones
Lipid profile
Fasting - No food/drink in 8 hours <126 mg/dL
Casual - <200 mg/dL
Urine ketones - high = hyperglycemia >300
HDL >50 LDL <130 Total <200
Oral Glucose Tolerance Test & Lab Values
- Gestational Diabetes
- Fasting, oral glucose, levels obtained every 30 min until 2 hours post consumption
- Fasting <110 mg/dL
- 1 hour - <180 mg/dL
- 2 hours - <140 mg/dL
HbA1C
Indicated for AVG glucose level over past 120 days (3 mos)
Used commonly for diagnosis and to evaluate effectiveness of interventions (meds/lifestyle)
Normal 4-6% Diabetic >6.5%
*Acceptable reference range for those w/ diagnoses DM, 6-8% range -> w/ target of 7%.
Blood Test Levels for Diagnosis: A1C
Normal: 4-6%
Pre-Diabetes: 5.7 - 6.4%
Diabetes: >6.5%
Blood Test Levels for Diagnosis: Fasting
Normal: 99 or below
Pre-Diabetes: 100 - 125
Diabetes: 126 or above
Blood Test Levels for Diagnosis: Oral Glucose Tolerance Test
Normal: 139 or below
Pre-Diabetes: 140 - 199
Diabetes: 200 or above
Diagnostic Criteria for T1D and T2D
T1D: islet cell antibody test
T2D: At least one of the following: - A1C 6.5 or higher - Fasting >126 - OGTT 200 mg - 3 Ps - Random glucose test of >200
Care for Pre-Diabetic Patient
Defined as impaired glucose tolerance, impaired fasting-glucose, or both.
No symptoms although long-term damage may already be occurring
Diagnostic criteria:
- A1C: 5.7 - 6.4
- Fasting: 100 - 125
- OGTT: 140 - 199
What can we do for these pts?
- Teach
- Lifestyle modification
- Close monitoring of A1C
- Monitor for s/s: fatigue, slow wound healing, getting sick
What medications are used more frequently in T2D patients?
Oral medications
Try to:
- Reverse insulin resistance
- Decrease insulin production
- Increase hepatic glucose production
What happens to hospitalized pts that are previously on oral diabetic meds?
They are put on insulin while acutely ill.
What do steroids do to your blood sugar?
Make it rise