Week 3(1) Atherosclerosis, Thrombosis, Embolism, Ischaemia and Infarction

Question 1

What is Ischemia?

Answer 1

Loss of blood supply to a tissue because of a blocked blood vessel.

This results in

• coagulative necrosis

Question 2

What is Infarction?

Answer 2

The death of a tissue (necrosis) SECONDARY to ischaemia followin abrupt interference with the blook supply.

Question 3

What are 2 TYPES of Infarction?

Answer 3

Arterial Infarction (WHITE)

• follows sudden obstruction, shaped according to the territory of blood vessel supply, PALE with red border in later states of scarring

Venous Infarction (RED)

• obstruction to venous drainage of organ or tissue
• ocngestion leading to rupture of the small vessels = RED

Question 4

What are the consequences of Infarction?

Answer 4

• insufficient oxgen
• insufficient nutrients
• excess waaste products

Question 5

So how does Ischemia affect the cells?

Answer 5

STASIS IS BASIS ;)

Cells like homeostasis. If there are SLIGHT changes the cells can adapt but if the changes are HUGE –> cell injury or death (necrosis)