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immunosero > week 23 > Flashcards

week 23 Flashcards

1
Q

The key cell involved in the immune response is
the .

A

lymphocyte

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2
Q

Lymphocytes represent between _________of the circulating white blood cells.

A

20 and 40
percent

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3
Q

The typical small lymphocyte:

A

✓ 7 and 10 μm in diameter
✓ has a large rounded nucleus that may be
somewhat indented
✓ nuclear chromatin is dense and tends to stain a
deep blue

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4
Q

PRIMARY LYMPHOID
ORGANS

A

 BONE MARROW
 THYMUS

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5
Q

◦ Largest tissue of the body (1300-1500g) in the adult.

A

 BONE MARROW

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6
Q

Fills the core of all long bones and is the main source of
hematopoietic stem cells

A

 BONE MARROW

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7
Q

w2e3i8ght o9f bo9ne3 mar4r4o9w2

A

1300-1500g

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8
Q

◦ T cells develop their identifying characteristics

A

THYMUS

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9
Q

Small, flat, bilobed organ found in the thorax, or chest
cavity, right below the thyroid gland and overlying the
heart

A

THYMUS

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10
Q

where is thymus found

A

found in the thorax, or chest
cavity, right below the thyroid gland and overlying the
heart.

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11
Q

thymus weighs

A

In humans, it weighs an average of 30 g at birth, reaches
about 35 g at puberty, and then gradually atrophies

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12
Q

SECONDARY LYMPHOID
ORGANS

A

 SPLEEN
 LYMPH NODES
 TONSILS
 APPENDIX
 MUCOSAL-ASSOCIATED LYMPHOIDTISSUE (MALT)
 CUTANEOUS-ASSOCIATED LYMPHOID TISSUE
(CALT)

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13
Q

Panels of antibodies from different
laboratories were used for analysis, and
antibodies reacting similarly with standard
cell lines were said to define

A

clusters of
differentiation (CD).

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14
Q

Types of T cells

A

1) helper T cells (CD4)
2) cytotoxic T cells (CD8)
3) suppressor T cells
4) memory T cells

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15
Q

B cell development

A
  • Pro-B cell
  • Pre-B cell
  • Immature B cell
  • Mature B cell
  • Activated B cell
  • Plasma cell
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16
Q

T cell development

A

Double-negative thymocytes
Double-positive thymocytes
Negative selection
Mature T cell
Activated T cell
 Sensitized T cell

17
Q

A small percentage of lymphocytes do not express the
markers of either T cells or B cells.

A

NK Cells

18
Q

These lymphocytes are generally larger than T cells and B
cells at approximately 15 μm in diameter, and they contain
kidney-shaped nuclei with condensed chromatin and
prominent nucleoli

A

These lymphocytes are generally larger than T cells and B
cells at approximately 15 μm in diameter, and they contain
kidney-shaped nuclei with condensed chromatin and
prominent nucleoli

19
Q

arise from the common lymphocyte precursor
(CLP) and differentiate into a T/NK cell that can become
either a T cell or an NK cell

A

nk cell

20
Q

is a receptor for the
fragment crystallizable portion, or nonspecific end, of the
immunoglobulin molecule IgG

A

CD16

21
Q

Fate of Antigen after Penetration

A

A. Through the blood stream
B. Through the Epidermal, Dermal or
Subcutaneous Tissue
C. Through the gastrointestinal or
respiratory tract

22
Q

Laboratory Identification of
Lymphocyte

A

 Cell flow cytometry
 Fluorescence microscopy
 Other methods: Rosette test

23
Q

Involves the
administration of vaccines to recipients.

A

ACTIVE IMMUNIZATON

24
Q

Bacterial vaccines contain intact
bacteria

A

Vaccines

25
Q

Prepared by killing cultured
organisms with heat or chemicals but must preserve
the immunogenecity of the preparation

A

◦ Killed bacteria

26
Q

Live attenuated bacterial vaccines –

A

Prepared by
frequent subculture on artificial media

27
Q

Bacterial materials vaccine –

A

Prepared from capsule,
pili or toxoids

28
Q

– consist of toxin neutralizing
antibodies that are specific for a given
toxin

A

Antitoxins

29
Q

 PASSIVE IMMUNIZATION

A
  1. Antitoxins – consist of toxin neutralizing
    antibodies that are specific for a given
    toxin:
    ◦ Commercial antiserum production
    ◦ Representative antitoxin
  2. Gamma globulins
  3. Specific Immune globulin
30
Q

most common
methods of administration

A

IM and SC injection

31
Q

– intracutaneous injection is used for
revaccination

A

ID

32
Q

for influenza
vaccinatio

A

Intranasal administration

33
Q

madami pa to kulang as appt di macopy patse lol

A

immunosero (2 decks)

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