Week 2: Smoking and smoking cessation

Question 1

Drugs for treating tobacco use

Answer 1

1. Nicotine replacement therapy
   - gum
   - patch
   - lozenge
   - inhaler: requires Rx
   - nasal spray: requires Rx
2. Craving reducers
   - Bupropion (wellbutrin): historically used as antidepressant
   - Varenicline (Chantix): blocks nicotinic Ach receptors, but can have mood/psych changes

Question 2

Second line medications

Answer 2

1. Nortriptyline
   - tricyclic antidepressant
2. Clonidine- a2 agonist
   - most monitor BP closely and taper when discontinuing