Week 2 - Sensory Changes with Aging Flashcards

1
Q

Age-related changes to the eye

A
  • lens gets opaque and stiff
  • cornea thickens, flattens, gets rigid
  • decreased density of cells of neural retina
  • degeneration of the sclera, pupil, iris
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2
Q

Presbyopia

A
  • normal age-related gradual loss of the eye’s ability to focus on close objects
  • noticeable as early as 40’s
    -caused by lens stiffness (no longer able to recoil as well when the ciliary muscles contract)
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3
Q

Presbyopia treatment

A

lens correction

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4
Q

4 pathological conditions of the aging eye

A
  1. cataracts
  2. glaucoma
  3. age-related macular degeneration
  4. diabetic retinopathy
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5
Q

Cataracts

A
  • opacity in the lens of the eye
  • crystallin misfolds and misfolded proteins aggregate (makes lens opaque)
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6
Q

Cataract symptoms

A

decreased acuity, hazy vision, increased sensitivity to glare, harder to see low-contrast

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7
Q

Cataract treatment

A

surgical removal of the lens and replace with a prosthetic lens

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8
Q

Age-related macular degeneration

A
  • loss of central field of vision
    dry and wet AMD
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9
Q

Dry AMD

A
  • most common
  • slow and progressive
  • build up of lipid deposits in the macula
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10
Q

Wet AMD

A
  • less common
  • can progress from dry AMD
  • growth of abnormal blood vessels that leak blood and fluid around the macula
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11
Q

Age-related macular degeneration treatment

A

no established treatment or reversing of vision loss
- ways to lower risk

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12
Q

Glaucoma

A
  • progressive optic nerve damage due to high intraocular pressure
  • results in permanent loss of peripheral vision (blindness if untreated)
  • open vs closed angle
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13
Q

Open-angle glaucoma

A
  • slow onset
  • raised intraocular pressure that damages the nerves of the retina and optic nerve
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14
Q

Closed-angle glaucoma

A
  • acute rapid onset
  • sudden blockage of fluid outflow (rapid elevation of intraocualr pressure)
  • serve pain, blurry vision, halos around lights
  • medical emergency and can lead to vision loss quickly
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15
Q

Glaucoma treatment

A

eye drops to relieve pressure

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16
Q

Diabetic retinopathy

A
  • damage to blood vessels of the eye due to chronic high glucose levels
17
Q

Initial stage diabetic retinopathy

A

microaneurysms form but are then absorbed

18
Q

Over time diabetic retinopathy

A

capillaries of the retina begin to leak fluid into tissue (edema of the retina)

19
Q

Late stage diabetic retinopathy

A

new blood vessel growth in the retina easily rupture, bleeding into eye (blindness)

20
Q

Diabetic retinopathy treatment

A
  • control blood glucose levels
  • laser to treat microaneurysms
  • surgically remove scar tissue
21
Q

Presbycusis

A

age-related hearing loss

22
Q

Sensorineural hearing loss

A

damage to sensory hair cells of the cochlea

23
Q

Presbycusis treatment

A

hearing aids, cochlear implants

24
Q

Tinnitus

A

perception of sounds in the absence of an acoustic stimulus

25
Q

Central auditory processing disorder (central presbycusis)

A

issues processing the neural stimuli
- linked to neurodegenerative diseases

26
Q

Link between hearing loss and dementia

A

untreated hearing loss is associated with accelerated cognitive decline and dementia

27
Q
A