week 2 review Flashcards
How do you diagnose acalasia?
manometry, due to an absense of distal gaglia in LES, cant diagnose it by upper endoscopy
What is CKIT +
GIST (gastrointestinal stromal tumors) tumors (receptor tyrosine kinase)PGDFRA mutations, tx gleevac
high folate low b12 and a hx of abdominal surgery is consistent with what disease pattern
small intestinal overgrowth
What is consistent with multinucleated cowdrie A type inclusions?
Herpes
Where does autoimmune gastritis occur?
Body and fundus of stomach
H. Pylori is associated with what conditions?
peptic ulcer disease, MALT lymphoma, gastric adenocarcinoma, inflammatory hyperplastic polyps
***Gastric adenocarcinoma genetics
wnt signaling (APC loss) and CDH1 gene loss
what is associated with gallstones
gallstone ileus, gallbladder cancer, choledocolithiasis, acute cholecystitis, acute pancreatitis, chronic cholecytsitis, and PSC
***histology findings of celiac disease
villous blunting, increased intrpid helical lymphocytes, lymphocytosis of the lamina propria
Enterohemorrhagic E. coli can cause what organ failure
kidney
can u kill giardia with clorine?
no
what is name of helminth infection
ascaris lumbricoides
where are the high risks of ischemic colitis?
splenic flexure, and recto sigmoid
*** what are three factors causing IBD
host interactions with intestinal microbiome
intestinal epithelial dysfunction
abberant mucosal immune response
genetics
what disease is highly associated with PSC
UC
Hamartomatous polyps
not cancerous but have associated syndromes that are associated with cancer peutz jegher and juvenile 40% risk
