Week 2 - Quantitive Genetics Flashcards

1
Q

Traits that are controlled by many loci of small effect are called -

A

Quantitive

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2
Q

Which traits fall into Quantitive genetics?

A

Height, weight, colour etc

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3
Q

What’s continuous variation?

A

A gradual change in characteristics across a population

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4
Q

What two values do heritability values range between?

A

0 - 1

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5
Q

What value does var (G) / var (P) give you an indication of?

A

Heritability

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6
Q

Which of the following are components of var (G)? Select all that apply.

Additive genetic variation

canalisation

dominance

epistatis

fluctuating assymetry

A
  • additive genetic variation
  • dominance
  • epistasis
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7
Q

What’s epistasis?

A

the effect of a gene mutation is dependent on the presence or absence of mutations in other genes

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8
Q

What does response to selection depend on?

A
  • heritability
  • selection differential
  • genetic interval
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9
Q

What’s genetic interval?

A

the average age of parents at birth of their offspring

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10
Q

Whats selection differential?

A

difference between the mean of the selected group and the mean of the population

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11
Q

How do you estimate the heritability of a trait?

A

Full sib/half sib analysis
Parent-offspring regression
Pedigree analysis
Selection experiments

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12
Q

If you perform a parent offspring regression, what value gives you the estimate of the heritability of the trait?

A

The slope of the line

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13
Q

What is the name of this equation? R= h2*S

A

Breeders Equation

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14
Q

What is the ultimate origin of genetic variation?

A

Mutations

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15
Q

What is it called when genotypes respond differently to environmental gradients?

A

Genotype by environment interactions

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16
Q

What mechanism maintains sickle cell anaemia?

A

Heterozygote advantage