Week 2, Morphine

Question 1

Morphine’s Pharmacologic Class: Opioid receptor agonist

Answer 1

Morphine’s Pharmacologic Class: Opioid receptor agonist

Question 2

What is Morphine’s Pharmacologic Class?

Answer 2

Opioid receptor agonist

Question 3

Morphine binds with both mu and kappa receptor sites to produce profound analgesia

Answer 3

Morphine binds with both mu and kappa receptor sites to produce profound analgesia

Question 4

What receptor sites does Morphine bind to?

Answer 4

Mu and Kappa

Question 5

What does Morphine produce after binding to Mu and Kappa receptors?

Answer 5

Profound analgesia

Question 6

Morphine relieves shortness of breath associated with heart failure and pulmonary edema, and for acute chest pain connected with MI.

Answer 6

Morphine relieves shortness of breath associated with heart failure and pulmonary edema, and for acute chest pain connected with M I.

Question 7

What does Morphine relieve?

Answer 7

Shortness of breath associated with heart failure and pulmonary edema, and for acute chest pain connected with MI.

Question 8

Pregnancy category B (D in long-term use or with high doses).

Answer 8

Pregnancy category B (D in long-term use or with high doses).

Question 9

What is Morphine’s Pregnancy category?

Answer 9

Pregnancy category B (D in long-term use or with high doses).

Question 10

Morphine may cause severe respiratory depression, and physical/psychological dependance.

Answer 10

Morphine may cause severe respiratory depression, and physical/psychological dependance.

Question 11

What can Morphine cause?

Answer 11

Morphine may cause severe respiratory depression, and physical/psychological dependance.

Question 12

Cross tolerance develops between morphine and other opioids.

Answer 12

Cross tolerance develops between morphine and other opioids.

Question 13

What develops between morphine and other opioids?

Answer 13

Cross tolerance.

Question 14

Morphine may mask the pain of gallbladder disease, due to biliary tract spams.

Answer 14

Morphine may mask the pain of gallbladder disease, due to biliary tract spams.

Question 15

What may Morphine mask the pain of?

Answer 15

Gallbladder disease, due to biliary tract spams.

Question 16

When morphine is administered as an epidural drug, patients must be observed in a fully equipped and staffed environment for at least 24 hours.

Answer 16

When morphine is administered as an epidural drug, patients must be observed in a fully equipped and staffed environment for at least 24 hours.

Question 17

How long should a patient be monitored after morphine is administered?

Answer 17

24 hours

Question 18

Drug-Drug reactions:
Concurrent use of CNS depressants such as alcohol, other opioids, general anesthetics, sedatives, and antidepressants such as monoamine oxidase inhibitors (M A O Is) and T C As, potentiate the action of opiates, increasing the risk of severe respiratory depression and death.

Answer 18

Drug-Drug reactions:
Concurrent use of CNS depressants such as alcohol, other opioids, general anesthetics, sedatives, and antidepressants such as monoamine oxidase inhibitors (M A O Is) and T C As, potentiate the action of opiates, increasing the risk of severe respiratory depression and death.

Question 19

Use of what in combination with morphine can cause respiratory depression and death?

Answer 19

CNS depressants, like alcohol and other opioids.