Week 2 - Krafts

Question 1

What are the two types of inflammation and what are the time frames for each?

Answer 1

1. Acute Inflammation: minutes - 48 hrs
2. Chronic Inflammation: >48 hrs

Question 2

What primary immune cells are prevalent in acute inflammation?

Answer 2

Neutrophils (pus!)

Question 3

What changes do blood vessels undergo in acute inflammation?

Answer 3

• Vessels dilate
• Increased permeability

Question 4

What do sections of tissue that have acute inflammation look like to Dr. Krafts?

Answer 4

• “BUSY”
• multisegmented nuclei
• many different sized black dots

Question 5

What are the three options tissue can undergo after 48 hrs of acute inflammation?

Answer 5

1. Neutrophils can form an abscess
2. Inflammation can heal
3. Progress to chronic inflammation

Question 6

What cells are prevalent in chronic inflammation?

Answer 6

• Mononucleate cells
  
  • Lymphocytes (viral)
  • Monocytes
  • Macrophages
  • Plasma cells

Question 7

What do sections of tissue that have chronic inflammation look like to Dr. Krafts?

Answer 7

• Uniform
• Round nuclei
• Very dark

Question 8

What does an abscess consist of?

Answer 8

• Neutrophils
• Debris

Question 9

What does a gross view of an abscess look like according to Dr. Krafts?

Answer 9

Round collection of greenish colored pus.

Question 10

What does a tissue section of an abscess look like according to Dr. Krafts?

Answer 10

• Large amount of mononucleate cells
• Necrotic tissue
• Engorged vessels

Question 11

How long can abscesses last?

Answer 11

a LONG time!

Question 12

What is the primary cell that reacts to tissue injury in the brain?

Answer 12

Astrocyte, duh

Question 13

What does an Astrocyte do in Gliosis?

Answer 13

• Proliferate
• Does the bulk of rebuilding following injury

Question 14

What is a Microglial Nodule?

Answer 14

Area where microglial cells surround dying tissue/neurons.

Question 15

What process involving the ventricular system can be a result of a CNS infection?

Answer 15

Hydrocephalus