Week 2: Isomers

Question 1

Define isomers?

Answer 1

Isomers have the same molecular formula bit different arrangements in space

Question 2

What are constitutional isomers?

Answer 2

Same molecular formula; different atom-to-atom connectivity

Question 3

What are stereoisomers?

Answer 3

Same atom-to-atom connectivity; different spacial arrangement

Question 4

x2 types of stereoisomers

Answer 4

1. conformational isomers
2. configurational isomers

Question 5

x2 types of configurational isomers?

Answer 5

1. enantiomers
2. diastereomers

Question 6

what are conformational isomers?

Answer 6

differ by rotation about a single bond

Question 7

what are configurational isomers?

Answer 7

interconversion requires breaking bonds

Question 8

what are enantiomers?

Answer 8

non-superimposable mirror images

Question 9

What are diastereomers?

Answer 9

not mirror images

Question 10

what compounds do we find cis/trans isomers in?

Answer 10

cyclic compounds

Question 11

cis or trans when substituents on sp3 carbon both above plane

Answer 11

cis isomers

Question 12

cis or trans when substituents on sp3 carbon 1 above and 1 below plane

Answer 12

trans isomers

Question 13

___ and ___ are relative terms

Answer 13

Cis and Trans
- substituent in relation to another

Question 14

what functional group contains E/Z isomers?

Answer 14

alkenes

Question 15

what type of bond fixes atoms in space?

Answer 15

pi-bond (no rotation about a pi-bond)

Question 16

E/Z isomers exist for alkenes under what condition

Answer 16

w≠x and y≠z

Question 17

What impacts interaction with other molecules (function)

Answer 17

molecular shape

Question 18

Feature of enantiomers to distinguish

Answer 18

non-superimposable mirror images

Question 19

Chirality and enzymes

Answer 19

different biological responses