Week 2 - Anxiety Disorders Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

What is the most common anxiety disorder?

A

Phobias

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the main 5 types of anxiety disorders?

A
  • Generalised Anxiety Disorder (GAD)
  • Specific phobia
  • Agoraphobia
  • Panic Disorder
  • Social Anxiety Disorder (social phobia)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the “specifiers” and why are they important

Give examples for anxiety

A

Extensions to a diagnosis to further clarify a disorder or illness. They allow for a more specific diagnosis.For research and clinical purposes.

  • Unspecified (and ‘other specified’) anxiety disorder
  • Anxiety due to another medical condition
  • Selective mutism & Separation anxiety (children)
  • Substance/Medication-induced Anxiety Disorder
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is anxiety?

A

Negative mood state characterised by bodily symptoms of physical tension and apprehension about the future.

  • Characteristic behaviours
  • physiological symptoms
  • subjective experiences
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Describe the DSM-5 clinical features of a panic attack

A

4 + features

  • Sweating
  • Chest pain or discomfort
  • Dizziness
  • Nausea or abdominal discomfort
  • Shaking or trembling
  • Chills, hot flushes
  • Palpatations, accelerated heart rate, pounding heart
  • muscle tension?
  • Sensations of shortness of breath/ smothering
  • Paraesthesia (pins & needles)
  • Fear of dying
  • Fear of “going crazy” or “losing control”
  • Depersonalisation (detached from one’s self) or Derealisation (detached from surroundings)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Describe the DSM-5 clinical features of a panic disorder

A

2+ panic attacks in a month?

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Describe the physiology behind anxiety, fear and panic attacks - note if it is related to a long term or acute response

A

The release of adrenaline

  • autonomic nervous system
  • acute fear response/ fight/flight
  1. Hypothalamic -Pituitary- Adrenal axis (HPA)
    - cortisol
    - acute response
    - longer term stress response
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the neurobiological risk factors for anxiety disorders

A

Neurotransmitters Systems

  • serotonin (decreased)
  • norepinephrine
    (noradrenaline) –> increased
  • GABBA (decreased)

Genetics + interactions with environment

Corticotrophin-releasing factor system
- Activates HPA Axis: over-
activation or breakdown in
negative feedback loop

Structure/function of brain regions
- Hippocampus & Amygdala,
limbic system, locus
coeruleus, prefrontal cortex

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are the personality-related risk factors for anxiety disorders

A

Behaviour Inhibition –> BIS/BAS
- strong predictor of social
anxiety

Neuroticism 
 - ^ reactions with negative 
 affect
 - ^ levels = strong predictor 
 for anxiety disorder
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the psychological risk factors for anxiety disorders

A

Behavioural
- Classical & operant
conditioning
- Modelling

Perceived control
 - Can stem from over- 
 protective/ helicopter 
 parents (depends on temperament of child & environment)
 - past trauma & perceived 
 control over event

Attention to threat
- Negative cues in environment - early trauma = more likely to see negative cues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the social factors for anxiety disorders

A
  • Familial
  • Stressors (70% report severe stressor before onset)
  • Exposure to stressors trigger vulnerabilities to anxiety
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the four major subtypes of phobias

A
  • Animals & insects (usually begins in childhood)
  • situational e.g. flying,
  • blood, injection, injury - (runs in families; heart rate slowing and possible fainting when facing feared stimulus)
  • Other e.g.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the four major subtypes of phobias

A
  • Animals & insects (usually begins in childhood)
  • natural environments e.g.
  • situational e.g. flying,
  • blood, injection, injury - (runs in families; heart rate slowing and possible fainting when facing feared stimulus)
  • Other e.g.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the four major subtypes of phobias

A
  • Animals & insects (usually begins in childhood)
  • natural environments e.g. storms, heights (usually begins in childhood)
  • situational e.g. flying, public transport, driving, confined spaces (usually begins in adolescence/
  • blood, injection, injury - (runs in families; heart rate slowing and possible fainting when facing feared stimulus)
  • Other e.g.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are the four major subtypes of phobias

A
  • Animals & insects (usually begins in childhood)
  • natural environments e.g. storms, heights (usually begins in childhood)
  • situational e.g. flying, public transport, driving, confined spaces (usually begins in childhood or mid-20’s)
  • blood, injection, injury - (runs in families; heart rate slowing and possible fainting when facing feared stimulus)
  • Other e.g.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the four major subtypes of phobias

A
  • Animals & insects (usually begins in childhood)
  • natural environments e.g. storms, heights (usually begins in childhood)
  • situational e.g. flying, public transport, driving, confined spaces (usually begins in childhood or mid-20’s)
  • blood, injection, injury - (runs in families; heart rate slowing and possible fainting when facing feared stimulus)
  • Other e.g. clowns, loud noises, contracting an illness
17
Q

What conditions tend to be comorbid with social anxiety?

A

Depression
Other Anxiety disorders
Alcohol abuse
Personality disorders

18
Q

What is the prevalence of panic disorder?

A

~5%

19
Q

What is the prevalence of social phobia & the gender ratio?

What is the common age of onset?

What are the two subtypes?

A

3-13%, 50:50 gender ratio

Adolescence

Performance only or generalised

20
Q

What is the prevalence of panic disorder?

Gender ratio?

onset?

A

~5%

2/3 female

Early adulthood (mid-teens-~40)

21
Q

What is the prevalence of GAD?

Gender ratio?

A

~5.7%

2/3 females (reporting bias?)

22
Q

Describe the process of the hypothalamic-pituitary- adrenal axis

A

Hypothalamus releases Corticotropin Releasing Hormone (CRH) to the pituitary gland –> pituitary gland releases Adrenocorticotropic Hormone ACTH to bloodstream —> ACTH reaches adrenal gland stimulating the release of cortisol —> cortisol initiates negative feedback mechanism on hypothalamus and pituitary gland

23
Q

Describe the process of the hypothalamic-pituitary- adrenal axis

A

Hypothalamus releases Corticotropin Releasing Hormone (CRH) to the pituitary gland –> pituitary gland releases Adrenocorticotropic Hormone ACTH to bloodstream —> ACTH reaches adrenal gland stimulating the release of cortisol —> cortisol initiates negative feedback mechanism on hypothalamus and pituitary gland —> end stress response

24
Q

What is the role of the limbic system in anxiety? (risk factor)

A
  • most implicated brain region in the risk of anxiety

- overly responsive to stimulation = abnormal bottom-up processing

25
Q

What is the role of the limbic system in anxiety? (risk factor)

A
  • most implicated brain region in the risk of anxiety
  • overly responsive to stimulation = abnormal bottom-up processing
  • Bottom-up processing begins with the retrieval of sensory information from our external environment to build perceptions based on the current input of sensory information
26
Q

What role does the amygdala have as a risk factor for anxiety?

A
  • Amygdala central involvement in anxiety (within the limbic system)
  • Recognises emotionally salient stimuli
  • Assigns emotional significance
27
Q

What role does the medial prefrontal cortex have as a risk factor for anxiety?

A
  • Decision making

- Fails to down-regulate (decrease in # of receptors on neurotransmitters) hyper-excitable amygdala

28
Q

What role does the medial prefrontal cortex have as a risk factor for anxiety?

A
  • Decision making
  • Fails to down-regulate (decrease in # of receptors on neurotransmitters) hyper-excitable amygdala
  • this leads to abnormal top-down processing (processing information based on prior knowledge)