Week 2 Flashcards
Day 8
▪️trophoblast continue to differentiate
-SCT produce hCG which is used in pregnancy tests and maintains corpus luteum therefore endometrial wall
▪️bi-laminar disc is distinct and flattens
-epiblast and hypoblast
▪️amniotic cavity is formed
Day 9-10
▪️implantation complete
-fibrin plug closes gap
▪️extracellular vacuoles appear in syncytiotrophoblast and join to form lacunae
▪️amnioblast separate from epiblast and organise into amnion (encloses amniotic cavity)
▪️formation of primary yolk sac surrounded by hypoblast
Day 11-13
▪️formation of extra-embryonic mesoderm
▪️formation of chorionic cavity surrounded by EEM
▪️primary yolk sack to secondary yolk sac
▪️maternal blood filled lacunae
-primitive utero-placental circulation
▪️formation of primary chorionic villi
Week 2 abnormalities
▪️abnormal implantation -uterine tube -outside uterus (ovary, bowel,GI) ▪️molar pregnancy -hydatidiform mole -trophoblast layers proliferate instead of epiblast- no embryo develops