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GI Exam 2 > Week 2 > Flashcards

Week 2 Flashcards

1
Q

Inherited mutation for Retinoblastoma

A

RB1

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2
Q

Inherited mutation for Familial Adenomatous Polyposis

A

APC

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3
Q

Inherited mutation for Neurofibromatosis type 1

A

NF1

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4
Q

Inherited mutation for Neurofibromatosis type 2

A

NF2

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5
Q

Inherited mutation for Li-Fraumeni Synd

A

TP53

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6
Q

Inherited mutation for Wilms Tumors

A

WT1

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7
Q

Inherited mutation for HNPCC

A

MLH1 and MLH2

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8
Q

Inherited mutation for famililal breat/ovarian cancer

A

BRCA1 & BRCA2

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9
Q

Inherited mutation for Multiple endocrine neoplasia

A

RET

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10
Q

Inherited mutation for Hepatocellular carcinoma

A

MET

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11
Q

DNA damage carcinogens

A

UV radiation, chems: tobacco, aflatoxin

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12
Q

Tumor promoting carcinogens

A

hormones, asbestos, viruses that cause chronic inflamm, H.pylori

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13
Q

Neural- Acetylcholine

A

Parasym cholinergic
smooth musc/glands
contract wall musc, relax sphincters, increase salivary, gastric and pancreatic secretion

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14
Q

Neural-VIP

A

parasym, cholinergic, enteric
Smooth musc glands
Relax sphincters, incre pancreatic and intest secretion

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15
Q

Neural- NE

A

symp, adrenergic
Smooth musc, glands
Relax wall muscle, contract sphincters, decreases salivary secretions

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16
Q

Neural- Neuropeptide Y

A

sympathetic adrenergic, enteric
Smooth musc, glands
Relax wall musc, decreases intestinal secretions

17
Q

Neural- GRP

A

parasym, cholinergic enteric
Glands
Increase gastrin secretion

18
Q

Neural- Subs P

A

parasym, cholinergic, enteric
Smooth musc, glands,
Contracts wall musc, increases salivary secretion

19
Q

Neural- Enkephalins

A

enteric
Smooth musc, glands
Constrict spincters, decrease intestinal secretions

20
Q

Paracrine- Histamine

A

ECL, mast cell
Stomach
Increase gastric acid secr

21
Q

Paracrine- Prostaglandin

A

cells lining GI tract
Mucosa
Increase blood flow, mucus and HCO3-

22
Q

Paracrine- Somatostatin

A

D-cells
Stomach and pancreas
Inhib peptide hormones and gastric acid secretions

23
Q

Hormonal-CCK

A

I cells
Pancreas, gallbladder, stomach,
Increase enz secr, contract gall bladder, incr gastric emptying

24
Q

Hormonal-Gluc-depend insulinopep (GIP)

A

K-cells
Pancreas, stomach
Releases insulin, inhibits acid secretion

25
Q

Hormonal- Gastrin

A

G-cells
Stomach
Increases gastric acid secretion

26
Q

Hormonal- Motilin

A

M cells
GI smooth musc
Increases contractions and migrating motor complexes

27
Q

Hormonal- Secretin

A

S cells
Pancreas, stomach
Releases HCO3- and pepsin

GI Exam 2 (3 decks)

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