Week 2 Flashcards by Ghislaine van der Lelie

Q

Frequency MODY-1

A

<10%

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Q

Frequency MODY-2

A

15-30%

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Q

Frequency MODY-3

A

50-65%

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Q

Frequency MODY-4

A

Rare

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Q

Frequency MODY-5

A

Rare

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Q

Frequency MODY-6

A

Rare

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Q

Genetic defect MODY-1

A

HNF-4-alpha

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Q

Genetic defect MODY-2

A

Glucokinasegen

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Q

Genetic defect MODY-3

A

HNF-1-Alpha

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Q

Genetic defect MODY-4

A

Insulin promotor factor 1

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Q

Genetic defect MODY-5

A

HNF-1-Beta

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Q

Genetic defect MODY-6

A

Neurogenid diff. factor 1

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Q

Beta cell defect MODY-1

A

Lower insulin secretion

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Q

Beta cell defect MODY-2

A

Sensing defect: glucokinase

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Q

Beta cell defect MODY-3

A

Lower insulin secretion

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Q

Beta cell defect MODY-4

A

Lower insulin secretion

Q

Beta cell defect MODY-5

A

Unknown

Q

Beta cell defect MODY-6

A

Pancreatic development

Q

Treatment MODY-1

A

Sulfonyluraes

Q

Treatment MODY-2

A

No/diet

Q

Treatment MODY-3

A

Sulfonylureas

Q

Treatment MODY-4

A

Insulin

Q

Treatment MODY-5

A

Insulin

Q

Treatment-MODY-6

A

Insulin