Week 14: Endocrine- Diabetes and Insulin therapy Flashcards

1
Q

Fasting blood glucose goal for diabetic patients?

HYPOGLYCEMIA is?

HEMOGLOBIN A1C LEVELS are?
goal A1C levels?

A

70-130

less than 70

3 month average
a goal A1C of less than 7

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2
Q

What does insulin do?

Hold Insulin when?
Hold meal insulin when?

A

Shifts potassium+ glucose from the blood into cells

If BG is <70
If patient is NPO

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3
Q

Rapid‑acting Insulin?
Short-acting Insulin?

Intermediate‑acting Insulin?
Long-acting Insulin?

A

Lispro insulin
Regular insulin

NPH insulin
Insulin glargine

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4
Q

3 Rapid‑acting Insulin?

Should look?

give when?

A

Lispro
Asparte
Glulisine

CLEAR

Give 15 min before meal or with meal
DO NOT give if food not here

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5
Q

Regular Insulin (OTC)

used for?

Should look?

How can it be given?

A

Diabetes
DKA
hyperkalemic emergencies

CLEAR

subq but can be used as continuous IV DRIP for DKA / HHS

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6
Q

Intermediate Insulin (NPH)

Should look?

A

CLOUDY INSULIN!!!

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7
Q

Long acting Insulin (Basal)

2 types?

Should look?

Given when?

A

Glargine and detemir

CLEAR

Once daily, commonly given at bedtime

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8
Q

Adverse effects of all Insulin

A

Hypoglycemia
-Peak is most dangerous time

Lipohypertrophy
-Happens from injecting same time
-rotate sites weekly
-Each day, rotate around ½-1 inch from previous site, then after 1 week, go to new site

Hypokalemia
-Seen with high doses
-We check potassium if on insulin drips

Weight gain
-They eat more and take more insulin
-More food is absorbed

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9
Q

Signs of hypoglycemia

Early signs?
Late signs?

A

Early Signs:
Confusion
Irritability
tremor, anxious, sweating, palpitations, cold

Late:
Hypothermia
Seizures

Cold and clammy, give em candy

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10
Q

Managing hypoglycemia

If patient is alert?
If patient is not alert?

“cold and clammy, give them candy”

A

Give 15 grams of carbohydrates (simple sugar)

Give IV dextrose (dextrose=glucose)
Or IM Glucagon

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11
Q

Insulin storage

Unopened?
Once opened?

A

-Keep it refrigerated

-Keep at room temp (don’t want cold vaccine in stomach)
-Must discard after 28 days

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12
Q

What insulins can u mix?

what insulin can u not mix?

NEVER SHAKE, always stir

A

ALWAYS NPH + regular OR rapid

NEVER mix NPH and true long acting

Do not mix rapid AND regular

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13
Q

Metformin

Adverse effect?
Potential for?

Boxed warning for?

A

GI issues ~20% N/D
Take with meals, start low, go slow

Potential for Vit B deficiency

LACTIC ACIDOSIS!!!
can happen in renal impairment, rare, but deadly

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13
Q

Draw 10 units of regular insulin and 15 units of insulin NPH in the same syringe. How?

NRRN

A

Step 1) Inject “15 units of air” in the NPH insulin vial

Step 2) Inject “10 units of air” in the regular insulin vial

Step 3) Withdrawal 10 units of regular insulin into a syringe

Step 4) Using the same syringe, withdrawal 15 units of NPH insulin

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14
Q

Metformin nursing considerations

When do u hold metformin?

A

If receiving contrast (media dye) , you MUST hold metformin for 48 hours AFTER procedure

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15
Q

Sulfonylureas:
GLIpizide
GLYburide
GLImepiride

it squeezes insulin out of pancreas

So what can happen?
No what?
can cause?

A

Hypoglycemia
-Take with food!!

weight gain (5-10 lbs.)
-Insulin makes u absorb more glucose

No ALCOHOL (EtOH)

Sulfa Allergy + Photosensitivity

16
Q

Sodium-Glucose Co-Transport 2 (SGLT-2) Inhibitors:

canagliflozin

Used for?
Makes u?

Side effects?
Give when?

A

DM2
Heart Failure (without diabetes!)

Pee out extra glucose

UTI
Hypotension
Increased urine output

Give in AM not PM

17
Q

GLP-1 receptor agonists:
exenatide, dulaglutide, semaglutide

Makes u feel?
Adverse effect?
BOXED WARNING?

A

Makes u feel full

GI- Nausea (44%), Vomiting, Diarrhea, Belching

increased risk for thyroid C-cell Tumors in rats and mice (both sexes)

take before meal

18
Q

Glucagon

Used to treat?

Is what?

A

Hypoglycemia

Is the Antidote

last line defense for hypoglycemia for unconscious patient