Week 13: Schizophrenia Flashcards

1
Q

Who introduced the term schizophrenia

A

Eugen Bleuler, in 1911

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2
Q

Schizophrenia is Greek for split mind. Split between ___ and ___ aspects of experience

A

Emotional and intellectual

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3
Q

The original term is ___ ___, which in Latin for ‘premature mental deterioration’.

A

Dementia praecox

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4
Q

True or false

Schizophrenia often occurs in women than in men

A

False

It occurs often in men

(A/N: hysteria = women, schizophrenia=men ayee jk)

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5
Q

True or false

The first diagnosis usually occurs in early adulthood, mild problems usually begin in childhood,
including deficits in attention, memory and impulse control.

A

True

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6
Q

Symptoms of schizophrenia (5).

A
  1. Delusions
    2.Hallucinations
    3.Disorganized speech
    4.Grossly disorganized behavior
    5.Weak emotional expression, speech, and socialization

(A/N: Must have at least two symptoms from the following list, including at least one of the first three)

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7
Q

There are two types of symptoms schizophrenia have, what are those (2)?

A

Positive symptoms and Negative symptoms

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8
Q

Symptoms that are present that should be absent in a person

Ex: delusions, hallucinations, disorganized speech, and disorganized behaviour

A

Positive symptoms

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9
Q

Symptoms that are absent behaviours that should be present in a person, generally stable over time, but difficult to treat

Ex: Weak emotional expression, speech, and socialization

A

Negative symptoms

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10
Q

True or False

A tendency for women who have a schizophrenic break-down during pregnancy to
give birth to daughters, and for women who have a breakdown shortly after giving
birth to have given birth to sons (Taylor, 1969).

A

True

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11
Q

An
uncommon type of schizophrenia that includes motor
abnormalities. A mixture of psychological and motor symptoms could represent
either schizophrenia or Huntington’s disease.

A

Catatonic schizophrenia

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12
Q

____ twins have have a higher concordance (agreement) for schizophrenia
than do ___ twins.

A

Monozygotic twins, dizygotic twins

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13
Q

The loss of a smallmpart of a chromosome

A

Microdeletion

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14
Q

Controls differentiation and migration of
neurons in brain development, production of dendritic spines , the generation
of new neurons in the hippocampus, and learning.

A

Distrupted in schizophrenia 1 (DISCI)

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15
Q

True or false

Genetics influence schizophrenia

A

True

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16
Q

Schizophrenia results at least in part from a dysfunction of glutamate transmission

A

Glutamate hypothesis of schizophrenia

17
Q

___ deficiency can produce hallucinations and delusions.

A

Niacin (vitamin B3)

18
Q

Differential Diagnosis of Schizophrenia

Someone with impaired hearing might think everyone else is whispering and worry, making delusions of prosecution develop.

A

Uncorrected hearing deficits.

19
Q

True or false

Brain damage or tumors in the temporal or prefrontal cortex can
produce some of the symptoms of schizophrenia

20
Q

Prenatal or neonatal difficulties of either genetic or
environmental origin can produce abnormalities in the
developing brain that predispose to schizophrenia (Weinberger,
1996).

A

Neurodevelopmental hypothesis

21
Q

Impairment and later symptoms of schizophrenia is the result of a combination of a genetic
predisposition and impacts from the environment in
prenatal/neonatal development, later in life, or both (Bayer et
al., 1999).

A

Two-hit hypothesis

22
Q

The tendency for people born in winter to
have a slightly increased probability of developing schizophrenia

A

Season-of-birth effect

(A/N: note to self, wag magpabuntis)

23
Q

True or false

Physical, emotional, or sexual abuse during childhood increases the risk and the
probable severity of later schizophrenia

24
Q

This parasite
reproduces only in cats, but people can be exposed to it by handling infected cats, by
playing in soil or sand where cats have defecated, or by eating chicken or pork after
those animals were fed in infected soil.

A

Toxoplasma gondii

25
Confinement in hospitals started in...?
1950
26
The antipsychotic drug __ relieves the positive symptoms of schizophrenia for most patients
Chlorpromazine (Thorazine)
27
Antipsychotic drugs occur in two chemical families: the ___, which include chlorpromazine, and the _____ which include haloperidol (trade name Haldol).
Phenothiazine and butyrophenones
28
This parasite does not always cross into the human brain, but if it does, it impairs a child’s brain development (Kramer and Bressan, 2015; Sutterland et al., 2015; Yolken et al., 2009)
Toxoplasma gondii
29
Drugs that block dopamine neurons in the mesostriatal system that project to the basal ganglia produces ___ , which is characterized by tremors and other involuntary movements
Tarditive dyskinesia
30
True or false Second-generation antipsychotics have less effect on dopamine receptors, but they also increase the release of norepinephrine .
False It increases release of glutae