Week 13- Bone disorders Flashcards

1
Q

What is dysplasia?

A

Presence of abnormal cells

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2
Q

What are different types (headings) of bone disorders?

A
  • Inflammatory bone diseases
  • Cystic lesions
  • Reparative lesions of bone
  • Nutritional Iatrogenic
  • Dystrophic bone diseases
  • Developmental
  • Hormonal
  • Hereditary bone diseases
  • Idiopathic
  • Tumours
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3
Q

What are characteristics of actinomyces?

A
  • In between bacteria and fungus
  • Can be associated with dental infections
  • Seen in third world
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4
Q

What questions do we need to ask for pt with disorder of bone?

A
  • What is it?
  • What causes it?
  • How do pts present/how do we find it?
  • How do we establish diagnosis?
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5
Q

What are the disorder headings for periodontal disease?

A
  • Infective
  • Inflammatory
  • Bone resorption
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6
Q

What is this?

A

Stafne’s bone cavity- below the IAN canal and bilateral.

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7
Q

How do we classify bone disorders on radiograph?

A
  • Anatomic
  • Artifact
  • Pathologic
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8
Q

How is radiographic appearance of bone described?

A
  • Radiopaque/radiolucent
  • Unilocular/multilocular
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9
Q

How are disorders of bone diagnosed?

A
  • Radiographic appearance
  • History
  • Exam
  • Imaging
  • Histopathology
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10
Q

What is Paget disease of bone (osteitis derformans)?

A
  • Dystrophic condition
  • More common in long bones but can happen in facial bone
  • 2 phases- resorptive phase, osteosclerotic phase (increased bone mass, disordered)
  • Can get heart failure
  • 4% progress to sarcoma
    Reversal lines
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11
Q

What are characteristics of osteopetrosis?

A
  • Bones are abnormally dense and prone to breakage
  • Loss of cortical definition
  • Dense calvaris
  • May present with hearing loss and sensory problems
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12
Q

What is cleidocranial dysplasia?

A
  • Developmental condition
  • Autosomal dominant
  • Effects bone undergoing intramembranous ossification
  • Dental abnormalities
  • Sinusitis
  • Mild developmental delays
  • Hypertelorism
  • No metopic suture
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13
Q

What are characteristics of fibrous dysplasia?

A
  • Bone replaced by fibrous tissue
  • Affects craniofacial bones
  • Painless enlargement- stops after adolescent
  • Genetic anomalies
  • Can associated with cutaneous/endocrine syndomes
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14
Q

What is this?

A

Fibrous dysplasia

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15
Q

What is osteomyelitis?

A
  • Inflammation of bone
  • +/- infection
  • Can be acute/chronic, suppurative or not
  • Can be pus
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16
Q

What is happening in this image and tx?

A

Osteomyelitis

  • Inferior border of right mandible- expansion.
  • Pathological
  • Well defined
  • Calcification within it surrounded by radiolucency
  • Dead primary teeth with chronic infection that has spread to bone marrow
  • Tx: excision of bone sequestrum
17
Q

What is this?

A

Osteomyelitis

18
Q

What are some common pathogens present in osteomyelitis?

A
  • Alpha-maeolytic strep
  • -ve staph
  • Priopionibacterium acnes
  • Actinomyces
19
Q

What is this?

A

MRONJ

  • Hard, yellow, exposed bone
  • Iatrogenic
20
Q

What condition does sterile bone inflammation mimic?

A

Mimic osteomyelitis on imaging and biopsy

21
Q

What are some autoinflammatory disorders of bone associated with?

A

Chronic recurrent multifocal osteomyelitis

(skin, gut disorders OR NSAIDS, MTX, antiresorptive agents)

22
Q

What is a mineral deficiency bone disorder?

A

Osteomalacia

22
Q

What is a mineral deficiency bone disorder?

A

Osteomalacia

23
Q

What are 2 hormonal bone conditions?

A
  • Osteoporosis (post-menopausal)
  • Hyperparathyroidism
24
Q

What are neoplastic disorders of bone?

A
  • Osteosarcoma
  • Chondrosarcoma
25
Q

What are characteristic radiographic features of osteosarcoma?

A
  • Sunray appearance
  • May see on OPG or CT
  • Expansion of periosteum
26
Q

What is happening in this radiograph?

A

Osteosarcoma OR may be old fractured md that did not receive tx

  • Loss of continuity of LHS md
  • Irregular replacement of proximal and distal ends
  • Lysis extending into bony stumps
27
Q

What is thalassemia?

A

Pt is anaemic bc haemoglobin synthesis is deranged