week 11

Question 1

SSRI

Answer 1

Mechanism: blocks reuptake of 5-HT → increased concentration in neuronal synapse

by blocking the reuptake of 5 HT then there is more serontinin in the system

Question 2

SNRIs

Answer 2

work similar to SSRI in blocking the reuptake of 5 hT

Question 3

TCA

Answer 3

5-HT & NE reuptake inhibition

Question 4

why are MAO inhibitors (MAOI) used for those with depression?

Answer 4

by blocking MAO –> leads to an increase NE and 5 - HT increase

Question 5

when dealing with antidepressants what do we want to increase the concentration of or block the reuptake of

Answer 5

5-HT and/ or NE

Question 6

what are three atypical antidepressants

Answer 6

Bupropion = mechanism uncles 
Mirtazapine = 5 HT and NE increased release 
Esketamine = NMDA receptor antagonist

Question 7

what is a first generation antipsychitotic

Answer 7

Conventional antipsychotics
Cheaper
Extrapyramidal symptoms

NEUROLEPTICS:
Primary mechanism (theory):
block dopamine receptor in mesolimbic
area of brain

Question 8

what is cheaper, a FGA or a SGA

Answer 8

FGA

Question 9

what leads to more EPS, FGA or SGA

Answer 9

FGA

Question 10

what would likely lead to weight gain or metabolic side effects - FGA or SGA?

Answer 10

FGA