week 1- uterine pathology Flashcards
another name for fibroids
leiomymoa
cause of leiomymoa
unknown
leiomyoma typically arise after menarche and regress after ___ implicating ___ as a promoter of growth
- menopause
- estrogen
leiomyoma (fibroids) are __ tumours
bengign
benign tumors of smooth muscle cells and fibrous CT, single or multiple and vary in size`
leiomyoma
Rate of occurrence for leiomyoma is markedly greater in ___ than ___
African American
whites
3 areas where leiomyoma affcets in the uterus
- intramural (within myometrium)
- submucosal (beneath endometrium)
- subserosal (serosal)
serosal surface of uterus projecting into the peritoneal cavity, including pedunculated myomas
subserosal (serosal)
types of leiomyoma (4)
- pedunculated
- submucosal
- subserosal
- calcified
symptoms of ___ include:
- menorrhagia (long bleed)
- spotting
- abdominal girth
- pain
- urinary frequency/ urgency
- low back pain
- leg discomfort/ swelling
leiomyoma
sonographic findings of leiomyoma
- heterogeneous myometrium
- irreg endometrial stripe
- hypoechoic areas in myo
- whorled internal architecture of mass
- calcifications
- posterior bladder contour change
what to do when requisition says: asymptomatic for leiomyoma
routine & FU
what to do when requisition says: large myomas and desire to become preg
myomectomy
what can the use of a prostaglandin or oral contraceptive do for leiomyoma
reduce eliminate symptoms bc control estrogen/progesterone levels
Pedunculated uterine leiomyomas occur when the fibroid is in continuity with the uterus. They may grow either ____ or ___
- within uterine cavity (submucosal)
- outside the uterus (subsersosal)
appearance of calcified myoma
echogenic
___ calcifications of the uterus image as echogenic foci in the periphery.
arcuate artery
if the location of the myoma is difficult to determine it is likely ____. However disruption of endometrium could result in categorization as a ____
- intramural (within myometrium)
- submucosal
within myometrium
intramural
beneath endometrium
submucosal
beneath the outer layer
subserosal
excessive growth of endometrium
endometrial hyperplasia
endometrial hyperplasia caused by
- high estrogen
- HRT (hormone replacement therapy)
- tamoxifen therapy
- diabetes
- obesity
- PCOD/ anovulatory cycles
t/f: endometrial hyperplasia increases womens risk for endometrial cancer and must be closely monitored
true
main cause of abnormal uterine bleeding
endometrial hyperplasia
upper limit endometrial thickness in premenopausal women
14mm
upper limit endometrial thickness in women on tamoxifen
10mm
upper limit endometrial thickness in postmenopausal women
8mm
Rx endometrial hyperplasia
- Hysteroscopy
- progesterone orally
- IUD (progesterone containing)
- hysterectomy
- D&C (dilation & curettage)
removal of uterus
Hysterectomy
sonographic finding of hyperplasia
- thickened endo
- homogeneous , hererogenic endo w/ small cystic areas
The findings of endo hyperplasia on US are nonspecific – a __ or ___ is necessary to confirm diagnosis
- biopsy
- D&C (scrape your uterus)
adhesion of the endometrium
Asherman’s Syndrome/ Synechia
synechia / asherman’s syndrome is due to
- trauma
- surgery
- c-section
- d&c