week 1 - reproductive hormones Flashcards

1
Q

what are the 15 reproductive hormones?

A
  • GnRH
  • LH
  • FSH
  • prolactin
  • oxytocin
  • estradiol
  • progesterone
  • testosterone
  • inhibin
  • activin
  • PGF2a
  • hCG
  • PGE2
  • eCG
  • placental lactogen
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2
Q

which hormones are neuropeptides?

A
  • GnRH
  • oxytocin
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3
Q

which hormones are glycoproteins?

A
  • LH
  • FSH
  • inhibin
  • activin
  • hCG
  • eCG
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4
Q

which hormones are proteins?

A
  • prolactin
  • placental lactogen
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5
Q

which hormones are steroids?

A
  • estradiol
  • progesterone
  • testosterone
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6
Q

which hormones are fatty acids?

A
  • PGF2a
  • PGE2
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7
Q

where does GnRH come from?

A
  • hypothalamus
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8
Q

where do LH and FSH come from?

A
  • anterior pituitary (gonadotrophs)
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9
Q

where does prolactin come from?

A
  • anterior pituitary (lactotrophs)
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10
Q

where does oxytocin come from?

A
  • synthesized in the hypothalamus (and corpus luteum in females)
  • stored in the posterior pituitary
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11
Q

where does estradiol come from in males?

A
  • sertoli cells
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12
Q

where does testosterone come from in males?

A
  • leydig cells
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13
Q

where do inhibin and activin come from in males?

A
  • sertoli cells
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14
Q

where does estradiol come from in females?

A
  • granulosa cells
  • placenta
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15
Q

where does progesterone come from in females?

A
  • corpus luteum
  • placenta
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16
Q

where does testosterone come from in females?

A
  • theca interna
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17
Q

where does inhibin come from in females?

A
  • granulosa cells
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18
Q

where does activin come from in females?

A
  • placental cells
  • granulosa cells
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19
Q

where does PGF2a come from in males?

A
  • vesicular glands
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20
Q

where does hCG come from in males?

A
  • trophoblast of blastocyst (chorion)
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21
Q

where does PGF2a come from in females?

A
  • endometrium
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22
Q

where does PGE2 come from in females?

A
  • ovary
  • uterus
  • embryonic membranes
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23
Q

where does hCG come from in females?

A
  • trophoblast of blastocyst (chorion)
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24
Q

where does eCG come from in females?

A
  • chorionic girdle cells
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25
Q

where does placental lactogen come from in females?

A
  • placenta
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26
Q

what is the target of GnRH in males and females?

A
  • anterior pituitary
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27
Q

what is the target of LH in males?

A
  • leydig cells in testis
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28
Q

what is the target of FSH in males?

A
  • sertoli cells in testis
29
Q

what is the target of prolactin in males?

A
  • testis and brain
30
Q

what is the target of oxytocin in males?

A
  • smooth muscle cauda
  • ductus deferens
  • ampulla
31
Q

what is the target of LH in females?

A
  • theca interna and CL in ovary
32
Q

what is the target of FSH in females?

A
  • granulosa cells in ovary
33
Q

what is the target of prolactin in females?

A
  • mammary cells
  • corpus luteum if you’re a RAT
34
Q

what is the target of oxytocin in females?

A
  • myo/endometrium
  • myoepithelial cells
35
Q

what is the target of estradiol in males?

A
  • brain
    • inhibits long bone growth
36
Q

what is the target of testosterone in males?

A
  • accessory sex glands
  • tunica dartos
  • seminiferous epithelium
  • skeletal muscle
37
Q

what is the target of inhibin and activin in males and females?

A
  • anterior pituitary (gonadotrophs)
38
Q

what is the target of estradiol in females?

A
  • hypothalamus
  • repro tract
  • mammary gland
39
Q

what is the target of progesterone in females?

A
  • hypothalamus
  • myo/endometrium
  • mammary gland
40
Q

what is the target of testosterone in females?

A
  • brain
  • skeletal muscle
  • granulosa cells
41
Q

what is the target of PGF2a in males?

A
  • epididymis
42
Q

what is the target of hCG in males?

A
  • fetal testis
43
Q

what is the target of PGF2a in females?

A
  • CL
  • myometrium
  • ovulatory follicles
44
Q

what is the target of PGE2 in females?

A
  • CL
  • oviduct
45
Q

what is the target of hCG and eCG in females?

A
  • ovary
46
Q

what is the target of placental lactogen in females?

A
  • mammary gland
47
Q

what is the action of GnRH in females and males?

A
  • increase FSH and LH
48
Q

what is the action of LH in males?

A
  • increase testosterone
49
Q

what is the action of FSH in males?

A
  • sertoli cell function
50
Q

what is the action of prolactin in males?

A
  • maternal behaviour
51
Q

what is the action of oxytocin in males?

A
  • PGF2a synthesis
  • pre ejaculatory movement of sperm
52
Q

what is the action of LH in females?

A
  • ovulation
  • CL function
  • progesterone secretion
  • follicle development
53
Q

what is the action of FSH in females?

A
  • follicle development
  • estradiol synthesis
54
Q

what is the action of prolactin in females?

A
  • lactation
  • maternal behaviour
  • CL function in some species
55
Q

what is the action of oxytocin in females?

A
  • uterin motility
  • PGF2a synthesis
  • milk ejection
56
Q

what is the action of estradiol in males?

A
  • sexual behaviour
57
Q

what is the action of testosterone in males?

A
  • anabolic growth
  • spermatogenesis
  • secretions of accessory sex glands
58
Q

what is the action of inhibin in males and females?

A
  • decrease FSH
59
Q

what is the action of activin in males and females?

A
  • increase FSH
60
Q

what is the action of PGF2a in males?

A
  • affect metabolic activity of sperm
  • epididymal contractions
61
Q

what is the action of hCG in males?

A
  • promote growth of fetal testis
62
Q

what is the action of PGF2a in females?

A
  • luteolysis
  • uterine horn tone and contractions
  • ovulation
63
Q

what is the action of estradiol in females?

A
  • sexual behaviour
  • GnRH production
  • secretory activity of tract
  • uterine motility
64
Q

what is the action of progesterone in females?

A
  • endometrial secretion
  • stop GnRH production
  • stop reproductive behaviour
  • maintain pregnancy
65
Q

what is the action of testosterone in females?

A
  • substrate for estrogen synthesis
  • abnormal masculinization
66
Q

what is the action of PGE2 in females?

A
  • ovulation
  • CL production of progesterone
67
Q

what is the action of hCG in females?

A
  • increase CL progesterone
68
Q

what is the action of eCG in females?

A
  • formation of accessory CL
69
Q

what is the action of placental lactogen in females?

A
  • mammary stimulation