WEEK 1 MEDS Flashcards
Morphine
analgesia, µ and κ receptors agonist
Codeine
Weak opioid, metabolized to morphine, has cough suppressing effect, for mild-to-moderate pain
Fentanyl
highly potent analgesic used in moderate-to-severe pain, used during anaesthesia, comes in various formats, including transdermal patch and lozenge
Methadone
long-half life thus risk of accumulation, monitor for dependence
Tramadol
Weak opioid
Naloxone
Used mainly for the treatment of overdose or for reversal of opioid depressant effects, opioid receptor antagonist
Paracetamol
non-opioid analgesic, helps to reduce the amount of opioids required to manage the same intensity of pain, has hepatotoxicity
Ibuprofen, celecoxib, indomethacin
non-opioid analgesic, Non-steroidal anti-inflammatory drugs (NSADS) > inhibits prostaglandin formation
Amitriptyline
Tricyclic antidepressants, adjuvant analgesics for neuropathic pain
Gabapentin, Pregabalin
anticonvulsants, adjuvant analgesics for neuropathic pain
Dexamethasone
corticosteroid, relieve pain associated with inflammation and swelling and space-occupying lesions (E.g. for cancer pain that originates in a restricted area
Midazolam, lorazepam
Benzodiazepines, pre-medication for general anaesthesia. Desired effects include: antianxiety, sedative, rapid induction, amnesia
Atropine
Anticholinergics > Inhibition of secretions
Ranitidine
H2-receptor antagonists, Reduce volume and acidity of stomach contents
Propofol
intravenous anaesthetics