Week 1 - Chapter 5 - Tissues Flashcards
What is the definition of Tissue in the context of cells and the body?
A group of similar cells with a common function (e.g. muscle tissue, epithelial tissue, connective tissue, nervous tissue, etc…).
What tissue is being described based on the following characteristics?
Function: Protection, secretion, absorption, excretion.
Location: Covering the body surface, cover and line internal organs, compose glands.
Distinguishing Characteristics: Lack of blood vessels, cells readily divide, cells are tightly packed.
Epithelial Tissue
What tissue is being described based on the following characteristics?
Function: Bind, support, protect, fill spaces, store fat, produce blood cells.
Location: Widely distributed throughout the body.
Distinguishing Characteristics: Mostly have good blood supply, cells are father apart than epithelial cells, with extracellular matrix in between.
Connective Tissue
What tissue is being described based on the following characteristics?
Function: Movement.
Location: Attached to bones, in the walls of hollow internal organs, heart.
Distinguished Characteristics: Able to contract in response to specific stimuli.
Muscle Tissue
What tissue is being described based on the following characteristics?
Function: Conduct impulses for coordination, regulation, integration, and sensory reception.
Location: Brain, spinal cord, nerves.
Distinguished Characteristics: Cells communicate with each other and other body parts.
Nervous Tissue
What are the 3 types of Intercellular Junctions?
Tight Junctions, Desmosomes, Gap Junctions.
Given the following characteristics and example, which Intercellular Junction is being described?
Characteristics: Close space between cells by fusing cell membranes.
Example: Cells that line the small intestine.
Tight Junction
Given the following characteristics and example, which Intercellular Junction is being described?
Characteristics: Bind cells by forming “spot welds” between cell membranes.
Example: Cells of the outer skin layer.
Desmosomes
Given the following characteristics and example, which Intercellular Junction is being described?
Characteristics: Form tubular channels between cells that allow exchange of substances.
Example: Muscle cells of the heart and digestive tract.
Gap Junction
What selects which chemicals are allowed to cross, protecting from toxins and chemical fluctuations?
Blood-brain Barrier
What are structures smaller than 100nm in at least 1 direction, that help medications cross the blood-brain barrier?
Example: Anesthetics of chemotherapeutics are combined with liposomes (phospholipid bubbles) to mask portion of drug that cannot cross the barrier OR Insulin can be inhaled in ultra small particles, instead of being injected.
Nanotechnology
Epithelial tissues have what on the outside, and what on the inside?
Free Surface / Basement Membrane
Based on the following Description, Function, and Location, what type of Epithelial Tissue is being described?
Description: Single layer, flattened cells.
Function: Filtration, diffusion, osmosis, covers surface.
Location: Air sacs of lungs, walls of capillaries, linings of blood and lymph vessels, part of the membranes lining body cavities and covering viscera.
Simple Squamous Epithelium
Based on the following Description, Function, and Location, what type of Epithelial Tissue is being described?
Description: Single layer, cube-shaped cells.
Function: Protection, secretion, absorption.
Location: Surface of ovaries, linings of kidney tubules, and linings of ducts of certain glands.
Simple Cuboidal Epithelium
Based on the following Description, Function, and Location, what type of Epithelial Tissue is being described?
Description: Single layer, elongated cells.
Function: Protection, secretion, absorption.
Location: Linings of uterus, stomach, and intestines.
Simple Columnar Epithelium
Based on the following Description, Function, and Location, what type of Epithelial Tissue is being described?
Description: Single layer, elongated cells.
Function: Protection, secretion, movement of mucus and substances.
Location: Linings of respiratory passages.
Pseudostratified Columnar Epithelium
Based on the following Description, Function, and Location, what type of Epithelial Tissue is being described?
Description: Many layers, top cells flattened.
Function: Protection.
Location: Superficial layer of skin and linings of oral cavity, vagina, and anal canal.
Stratified Squamous Epithelium
Based on the following Description, Function, and Location, what type of Epithelial Tissue is being described?
Description: 2 or 3 layers, cube-shaped cells.
Function: Protection.
Location: Linings of ducts of mammary glands, sweat glands, salivary glands, and pancreas.
Stratified Cuboidal Epithelium
Based on the following Description, Function, and Location, what type of Epithelial Tissue is being described?
Description: Top layer of elongated cells, lower layers of cube-shaped cells.
Function: Protection, secretion.
Location: Part of the male urethra and lining of larger ducts of excretory glands.
Stratified Columnar Epithelium
Based on the following Description, Function, and Location, what type of Epithelial Tissue is being described?
Description: Many layers of cube-shaped and elongated cells.
Function: Stretchability, protection.
Location: Inner lining of urinary bladder and linings of ureters and part of the urethra.
Transitional Epithelium
These general characteristics describe what type of tissue?
Most abundant by weight.
Farther apart than Epithelial cells.
Contain abundant extracellular matrix between cells, consisting of protein fibers and a ground substance.
Consistency varies from fluid to solid.
Most cells have the ability to divide.
Most have a good blood supply so they are well-nourished.
Contain Fixed Cells which remain in one place, and Wandering Cells like macrophages that move throughout tissues.
Connective Tissue
What are the two categories of Connective Tissue?
Connective Tissue Proper / Specialized Connective Tissues
What are the 8 functions of Connective Tissues?
- Bind structures together.
- Provide support and protection.
- Serve as frameworks.
- Fill spaces.
- Store fat.
- Produce blood cells.
- Protect against infections.
- Help repair tissue damage.
What is considered “The Body’s Glue”?
The Extracellular Matrix
What are the functions of the Extracellular Matrix?
Organizes and anchors cells to tissue, relay chemical signals that control cell division, differentiation, repair, and migration.
CLINICAL APPLICATIONS EXAMPLE
What can convert fibroblasts into myofibroblasts, loosen fibroblast connections, which allow for the migration of converted fibroblasts and spreading?
Cancer
CLINICAL APPLICATIONS EXAMPLE
What is it when collagen deposition increases, and ECM exceeds the normal 3% of the organ? Damaging agents will evoke a normal inflammatory response but if it continues too long then it can block the connection between liver cells and blood, potentially leading to cirrhosis.
Liver Fibrosis
CLINICAL APPLICATIONS EXAMPLE
Some forms involve excess collagen deposition, which can stiffen the heart or block blood flow.
Heart Failure and Atherosclerosis