week 1-7 Flashcards
Traditional model
- one way causation- pathogen to the host
- nonhiearchical-different levels do not interact
- physiological process
- dualistic
Biobehavioral Model
- informational interchanges(thoughts about the disaese-cure)
- exchange of information( host and pathogen)
Descartes
- reductionist(saat ornegi)
Stress
“a bodily or mental tension
resulting from factors that tend to alter an existent equilibrium
* compensation
* mismatch between perceived demands and
resources
Hans Selye
- father os stress
- universal stress response pattern
general adaptation syndrome(sELYE)
alarm
resistance
exhaustion
enlargement of adrenal gland(adrenaline/epinephrine
Systems theory
brain constantly integrates information
hierarchically to regulate bodily
functions
interoceptive(within body)regulation unconscious
Perceived threat stimulus
- autonomic or endocrine responses to
change physiological processes in the body - behavioral responses to change the
environment
transactional model of
stress and coping
- Cognitive appraisal - any event is potentially
a stressor - Primary appraisal (perceived demands):
(threat / challenge value),
beliefs and commitment - Secondary appraisal (resources):
Personal belief of capacity to reduce the stressor, by
considering internal and external resources and
coping potential
acute(adaptive )s response
- catecholamines (e.g., adrenaline)
- glucocorticoids (e.g., cortisol)
- increased energy
stress-related (cortisol production) areas
- hippocampus
- amygdala
- Medial prefrontal
- orbifrontal cortices
Gate Control theory & Neuromatrix model of pain
- multidimensional experience
- widely distributed n
- somatic sensory input is only a part
Amygdala sensitization
increased hpa activity
Somatic sensitization
- habituation (reduced response) → under conditions of low arousal
- sensitization (amplified response) → under conditions of high arousal (e.g.,
stress)
somatic sensitization
allodynia-hyperalgesia
- allodynia(normalde acitmayan seyler acitiyor)
- hyperalgesia(daha cok canin yaniyor)
Stress-related emotions
- increased noradrenaline
- increases pain more for fibromyalgia show the same autonomic nervous system response to anger
and sadness than healthy women, but only in
patients this response is associated with pain
anterior cingulate cortex
area for pain but also activated during social exclusion
somatic
amplification
isci hastaneye kaldirilir civi batmadigi anlasilir ama cani cok acimmistir.
Cognitive sensitization
- More attention to and detection of internal & external pain cues
- Ambiguous internal and external information interpreted in terms of pain
- missattribution of harmless signals as pain
- More and stronger pain memory traces
Pain-related cognitions
- fear of pain
- hypervigilance (strong attention to pain stimuli)
- worrying(what iff)
- catastropizing( exaggerated orientation)
Chronic peripheral resistance
→ high blood pressure(prolonged)
→ cardiovascular disease
Animals-humans
- animals-decreased immune response for short catstrophic stress(shock)
- humans- increased immune response for acute stress
- acute uncontrollable/ chronic stress- dysregulated immune system -low-frade inflammation .overactivation over time.
Optimism
- Negative outcomes: unstable/specific/external
- Positive outcomes: stable/global/internal
heart rate rectors
higher reactor hs more increase in cortisol but they subjectively evaluate of the stressor