week 1 Flashcards
Why is it called primary GINGIVOSTOMATITIS?
Due to the site of lesions on the gingiva
AND/OR on ANY: oral mucosa
secondary HSV
- age
- systemic
- oral 1 (3 locations)
Age: Usually puberty and after…
Systemic: none
Oral: Vesicles->ulcers
located: 1. Gingiva 2. Hard palate 3. Lips
Differential diagnosis HSV primary (3)
Streptococcal Pharyngitis
Erythema multiforme
ANUG
Differential HSV primary (3) reasons it is not each
- SP (1)
- EM (4)
- AN (3)
Strep- Pharyngeal (posterior lesions) palate/post mouth
Erythema Multi- requires a sensitivity (usually very immediate timing. Target lesion. LARGE crusty lesions on LIP/Buccal mucosa NOT ON GINGIVA!!!!
ANUG-STENCH, [Bleeding gums w/o brushing], commonly has stress or immunocompromised host]
Treatment for Diff diagnosis HSV
(3)
SP EM ANUG
Strep- Streptococcal antibiotics
Erythema Multi- Steroids for type 3/2 hypersens.
ANUG- Oral hygeine and ANUG specific Antibiotics
Differential Diagnosis for HSV secondary
- disease
- Reason it is not (3)
Aphthous ulcers
- No tingling prodromal phase
- Non-keratinized tissue ONLY!!!!
- Never has a vesicle or bulla prior to the ulcers
What is a cause for secondary HSV lesions to not be restricted to Ging, Hard palate, or lips? (2)
Immunocompromised - AIDS etc
Chemotherapy
What are 4 ways to determine HSV diagnosis if the clinical signs are insufficient?
- Biopsy (painful and invasive)
- Fluorescent antibody test (via smear) can be inconclusive with other similar viral DNA (Herpetic family etc)
- Insitu hybridization (expensive)
- Culture (1-3 days)
Pro / con of Biopsy vs smear cytology
Biopsy is invasive/painful
Smear will not show tissue architecture (may be inconclusive or lack specificity)
Tzanck (z-(t)ank) Tank but starts with a z sound…
-indicates it could be what possible diseases? (4)
HSV VZV Cytomegalovirus or Pemphigus vulgaris (common pemphigus)
Describe a Tzanck cell (2)
-what cells are they initially?*
Balloon and glassy
-initially prickle cells of epithelium (obviously of Keratinized tissue)
What is the primary systemic concern for prescribing valtrex for a viral infection?
Kidney function
Supportive care for Primary HSV infection: non-immunocompromised (4) and if fever 1 more (children vs adults)
- Rest
- Fluids
- Soft food
- Xylocaine 2%
* Fever
5c. Tylenol (often children so no aspirin)
6a. Aspirin (adults)
What timing window must be met before giving medication for any HSV?
48 hrs of onset of prodromal symptoms (tingling)
Can we treat a patient for a TOOTH problem if they have an active secondary HSV infection?
-Why might you not treat?
CAREFULLY and only if they have an emergent issue.
- otherwise reschedule them
- -We do not want to spread the involved tissues to another area of the patients face or mouth