Week 1 Flashcards

Mendelian Genetics and Probability

1
Q

what are the 2 types of genetic selection

A

natural or artificial

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2
Q

define: domestication

A

purposeful mating of individuals with desirable phenotypes for greater expression of those characteristics in offspring

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3
Q

when did dogs first occur

A

~15,000 years ago

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4
Q

when did the domestication of pigs, goats, sheep, and cattle occur

A

~10,000 years ago

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5
Q

how are dogs and wolves related

A

they have the same genes

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6
Q

what species did Dmitry Belyaev perform experiments on

A

silver foxes

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7
Q

how are silver foxes and red foxes related

A

silver foxes are a recessive phenotype

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8
Q

what did Belyaev prove in terms of the behaviour of silver foxes

A

their behaviour remained intact even when they were raised by mothers of the opposite breed

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9
Q

when were crops domesticated and where

A
  • ~13,000 years ago
  • in the Middle East
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10
Q

what are true-breeding lines

A

breeds where offspring carry parental traits that remain constant from one generation to the next

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11
Q

what plant did Mendelian use to study genetics

A

garden peas

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12
Q

define: phenotype

A

observable characteristic (commonly referred to as a trait)

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13
Q

define: genotype

A

genetic make-up, description of the genetic information carried by an individual

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14
Q

how is self-fertilization prevented when performing cross-fertilization

A

the anthers (producer of pollen/male gametes) is removed

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15
Q

what does reciprocal cross-fertilization mean

A

2 organisms of different genotypes are mated in 2 ways
1. Male (Parent A) x Female (Parent B)
2. Male (Parent B) x Female (Parent A)

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16
Q

is each seed of a garden pea genetically identical

A

no, each seed can have a different genotype

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17
Q

what is a true-breeding line

A

the offspring always show the same phenotype as the parent plants

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18
Q

define: monohybrid cross

A

the mating of true-breeding parents with antagonistic traits (only 1 differing trait) [Ww]

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19
Q

define: P generation

A

parental: it is the first generation in the breeding experiment

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20
Q

define: F1 generation

A

first filial: first offspring of the P generation

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21
Q

define: F2 generation

A

second filial: derived from the interbreedings of F1

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22
Q

is it possible for the a lost trait (e.g. breeding tall and dwarf plants resulting only in tall plants) to reappear

A

yes

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23
Q

define: alleles

A

alternative forms of a single gene

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24
Q

what are discrete units of inheritance

25
define: homologous chromosomes
chromosomes with the exact same genes that have different alleles
26
how are genes/alleles notated
with italics
27
what genotype does *WW* represent
homozygous dominant
28
what genotype does *Ww* represent
heterozygous
29
what genotypes does *ww* represent
homozygous recessive
30
define: polymorphic gene
gene with several alleles that normally occur in a population
31
define: monomorphic gene
gene that has only one allele normally present in a population (however other alleles can exist!)
32
how many alleles for one gene can exist in a diploid individual
a maximum of two
33
what is the law of segregation
two alleles for each trait separate during gamete formation, then unite **at random**, one from each parent, at fertilization
34
what is the phenotypic ratio for a heterozygous cross [*Ww* x *Ww*]
3:1
35
what is the genotypic ratio for a heterozygous cross [*Ww* x *Ww*]
1:2:1
36
what does it mean to be a dominant/recessive trait at the DNA level
no conclusions can be made
37
which gene is there a mutation for in wrinkled peas
SBE1, starch-branching enzyme 1 SBE1 in inactive due to the mutation
38
what does the inactivity of SBE1 lead to
starch doesn't branch, leading to an excess of water in young peas, and the loss of water once they mature
39
what genotype do you use when conducting test crosses
homozygous recessive
40
what is another way of conducting test crosses for some organisms
self-fertilizing
41
what is the law of product
the probability of two or more independent events occurring together is the product of the probabilities that each event will occur itself [probability of *aa* from a cross of *Aa* and *Aa* is 1/2 x 1/2 = 1/4]
42
what is the law of sum
the probability of either of two mutually exclusive events occurring is the sum of their individual probabilities [probability of producing a yellow pea (dominant) from a cross between heterozygous plants is (1/2 x 1/2 )|*GG*| + (1/2 x 1/2)|*Gg*| + (1/2 x 1/2) |*gG*|]
43
define: dihybrid cross
mating between individuals that differ in two traits, where alleles of 2 genes act independently in a dominant and recessive manner [*GgWw*]
44
is it possible for new phenotypic combinations to appear from a monohybrid cross
traits may reappear, but no new ones appear
45
is it possible for new phenotypic combinations to appear from a dihybrid cross
yes
46
how do the law of segregation and the law of independent assortment differ
law of segregation - how different **alleles** of a gene behave law of independent assortment - how different **genes** behave
47
what is mendel's law of independent assortment
during gamete formation, different pairs of alleles segregate independently of each other
48
know how to draw a branching diagram [e.g. *GgWw* x *GgWw*]
should end up with: 1/16 *GGWW* 2/16 *GGWw* 1/16 *GGww* 2/16 *GgWW* 4/16 *GgWw* 2/16 *Ggww* 1/16 *ggWW* 2/16 *ggWw* 1/16 *ggww*
49
what are the phenotypic rations for a *GgWw* x *GgWw* cross [yellow/green, round/wrinkled]
9/16 *G_W_* 3/16 *G_ww* 3/16 *ggW_* 1/16 *ggww*
50
how many test cross possibilities are there to find the genotype of a yellow, round pea
4
51
define: multihybrid
matings between individuals that differ in three or more traits [e.g. *AaBbCcDd*]
52
what is the probability of an *AAbbCcDd* offspring from a *AaBbCcDd* x *AaBbCcDd* cross (use the law of product and genotypic ratios!)
1/4 x 1/4 x 1/2 x 1/2 = 1/64
53
which law allows you to treat alleles of a single gene independently
law of segregation
54
which law allows you to treat different genes separately
law of independent assortment
55
what is the probability of an *aaBbCcDd* offspring from a *aaBbCCDd* x *AaBbccDD* cross
1/2 x 1/2 x 1 x 1/2 = 1/8
56
define: continuous trait
trait with many intermediate forms [e.g. skin colour]
57
define: discrete trait
trait with no intermediate forms [e.g. yellow or green peas]
58
define: parental type
F2 progeny that look like one of the parents
59
define: recombinant type
F2 progeny with new phenotypic combinations