Week 1 Flashcards
Who is Hippocrates
The father of medicine oi
HISTOPATHOLOGy meaning
Histo: Tissue
Pathos: Suffering/Disease
Logos: Study
Sir William Osler - father of modern medicine
Pathologists contribute to patient management by providing final diagnosis of disease’.
- he is the first guy to say so see people and learn from clinical trials
General Histopathology
Is concerned with the reactions of cells and tissues to abnormal stimuli and
to inherited defects, which are the main causes of disease.
It is an understanding of variation between normal and abnormal tissue
Oral Histopathology
Is a branch of dentistry that deals with the identification, nature, and
management of diseases affecting the oral and maxillofacial region.
What is a disease
Abnormal variation instructure and size
What are the 2 types of disease
Acquired disease d caused from exposure to environmental agents
Congenital disease is genetically determined
What are 4 aspects of disease process
- Etiology, origin I why the disease occurred
- Pathenogenisit - mechanism/ steps of development’l now it happened
- Morphological changes - structure, shape, size changes
- Clinical manifestation - functional consequences
What it patient
The person affected by disease
What is ethology
The cause of the disease
Pathogenesis?
The mechanism of development or the sequence of events that follow the exposure of cello tissue to an injourus agent
Morphological charges?
The structural alterations induced in cells, tissues, organs o- macro + microscopio
Idiopathic
The desease it without an evidente cause, leve auto inmune disease
Secondary
• The disease represents a complication or manifestation of an underlying condition
e.g. Nephropathy in diabetic patients
Acute
Conditions that have a rapid
onset
e.g. Appendicitis, periapical abscess
Chronic
Conditions of insidious onset & have a prolonged course lasting for months or years e.g. pyogenic granuloma
Symptoms
What the patient perceives to be
wrong
Signs
• What the clinician perceives to be
wrong
e.g. a lump or skin rash
Diagnosis
Recognition of a disease by the
signs
and symptoms
Treatment
Methods used to manage disease process
Prognosis
Probable outcome or likely course of the disease
Complications
Secondary or distant effects of the disease
Remission
The conversion from active disease to quiescence (inactive
state/ dormancy)
Relapse
The reappearance of signs & symptoms
Histopathology
The investigation and diagnosis of disease from
the examination of tissues. E.g. tumors
Cytology
The investigation and diagnosis of disease from the examination of isolated cells. e.g. Smear from the oral cavity
Hematology
The study of disorders of the cellular and coagulable components of blood. E.g. Hemophilia (deficiency of factor VIII)
Microbiology
The study of infectious diseases and the organisms
responsible for them. e.g. mycobacterium tuberculosis
Immunology
The study of the specific defense mechanisms of the body
e.g. Studying antibody levels
Genetics
The study of abnormal chromosomes and genes
Toxicology
The study of the effects of known or suspected
poisons/drug abuse
Forensic Pathology
The application of pathology to legal purposes (e.g. the investigation of death in suspicious circumstances)