Week 1 Flashcards
Drug source: Botanical
plant based
Drug source: animal
Hormones
old method of harvesting
Drug Source: Electrolytes
Synthesized
most modern drugs are made in labs
Binders
Stick together
Coatings
Will not interact with the stomach
preservatives
help keep longer on shelves
Thickeners
paste, syrup
Pharmacotherapeutics
Treatment using medication
Technicians role in regimen
Technicians must:
verify drug
calculate and confirm dosage
administer by correct route and time
observe animals response
question unclear med orders
ensure accurate labels
client education
create legal record for the regimen
Rx
prescribed by doctor
OTC
over the counter
Veterinary-Client-Patient relationship
federal legal requirement for the prescription of drugs
Extralabel use
Vetrinarian may choose a drug for treatment even if that drug is not labeled for that species or disease
Veterinarian-Client-Patient relationship required
Controlled substances
drugs that have potential for abuse or dependence
stored in locked storage
Pharmacokinetics
Events that occure after drug is administered to a patient
Routes of administration
vary by drug and desired effect
enteral- usually by mouth
parenteral injection- not digestive system
Inhalation- breathable meds
topical- surface
Bioavailability
how much of the drug is absorbed
Drug distribution
how a drug gets from the absorption site to the site of action
Biotransformation
metabolism
how the body changes to the drug so it can be excreted
Drug excretion
how/where the drugs are exctreted from the body
half-life
time required to excrete half of the present amount of the drug
Residue
drug that can not be fully excreted leaves a residue in the body
Pharmacodynamics
mechanisms by which drugs produce physiologic changes in the body
agonist
ability to bind with a receptor
partial agonist
ability to bind to parts of a receptor
antagonist
blocks a receptor so that it cannot be bound
efficacy
how well the drug produces the effect we want
LD50
lowest dose that is lethal to 50% of animals in a trial
ED50
lowest dose that produces the desired effect in 50% of animals in a trial
Therapeutic Index
drug’s ability to acheive the desired effect and its tendency to produce toxic effects
adverse reaction
An undesirable response to a drug
mild - life threatening
Drug Interactions
response to a drug that is caused by the presence of a second drug
FDA
CVM
food and drug administration
center for veterinary medicine
regulates animal drugs and feed additives
EPA
Environmental Protection Agency
regulates animal topical pesticides
USDA
U.S. Department of Agriculture
regulates biologics
FARAD
Food Animal Residue Avoidance Databank
database used to check if it is ok to use
The Green Book
list of animal drugs approved by the FDA
AMDUCA
The Animal Medicinal Drug USe Clarification Act of 1994
Allows extralabel use of drugs by vet prescrtiption
MUMS
The Minor Use and Minor Species Animal Health Act of 2001
allows extralabel approved drug use in less common species