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MCB 325 > Week 1 > Flashcards

Week 1 Flashcards

1
Q

which group of people developed scrotal cancer in the late 1700’s

A

english chimney sweepers

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2
Q

which group of people developed tongue cancer in the 1920s

A

women who painted luminescent radium on wristwatches

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3
Q

what is a mutagen

A

agent that causes alterations to DNA

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4
Q

what is a carcinogen

A

cancer causing agent

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5
Q

how can cancer come from a viral infection

A

someone contracts the virus, the virus has an active oncogene, causes cancer in the new organism

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6
Q

what is an oncogene

A

a gene that can cause cancer when mutated or altered

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7
Q

what is a tumor suppressor

A

a gene that normally suppresses cancer growth but is inactivated when mutated or altered

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8
Q

what is the most common type of cancer

A

cancer of the epithelium

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9
Q

what is the 2nd most common cancer

A

cancer of connective tissues

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10
Q

what is the 3rd most common cancer

A

muscular cancer

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11
Q

what is the rarest form of cancer

A

nervous tissue cancer

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12
Q

what is the function of epithelial tissue

A

lines cavities and surfaces of the body

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13
Q

what are examples of connective tissue

A

fibroblasts, blood cells, and adipose tissue

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14
Q

what is the repair for bulky adducts and pyrimidine dimers

A

nucleotide excision repair NER

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15
Q

what is the repair for abasic site, uracil, and single strand break

A

base excision repair

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16
Q

what is the repair for double strand break, inter strand cross link

A

homogulous recombination HR, or nonhomogulous end joining NHEJ

17
Q

what is the repair for base pair mismatch

A

mismatch repair

18
Q

tight junction function

A

separate apical and basolateral membranes

19
Q

adherens junction function

A

provide mechanical signal to epithelial cells that cells are healthy

20
Q

desmosomes function

A

adhere cells to each other and provide a link to intermediate filaments

21
Q

hemi-desmosomes function

A

adhere cells to basement membrane

22
Q

what is hyperplasia

A

cells act normally but divide too much

23
Q

what is metaplasia

A

cell is still normal but becomes a different normal cell

24
Q

what is dysplasia

A

cells are normla but are in the wrong place in the tissue

25
Q

what is neoplasia

A

they have passed the basement membrane

MCB 325 (3 decks)

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