Week 1 Flashcards
nephrotic syndrome surprisingly includes
hypercoag leading to risk of renal vein thrombus
drugs turning pee red
macrobid and rifampin
parasite causing hematuria
schistosomiasis - eggs laid in Gu cells - 15% of people is some areas of africa - 150,000 deaths, common cause of CKD
bleeding issues in CKD
platelet dysfunction from uremia, needs dAVP
Branham sign
occlude AV fistula, get drop in HR, indicates high output heart failure on a dialysis patient from the AV fistula
PD related peritonitis
100WBC and 50% neutrophils. this is lower than the 250 neutophil cutoff for sbp in cirrhosis
stagnorn stones
made of struvite, klebliessa making urea stones
radio-lucent stones
uric acid stones - gout, leukemia, high protein diets
prostatitis and epididymitis treatment
under 35 tx like PID - ceftriaxone IM and doxy for 10 days. over 35 tx with bactrim for 2-4 weeks for e coli
lymphogranuloma venereum -
chlamydia, painless ulcer then inguinal adenopathy with pus possible, tx with doxy.
prehn sign
relief of pain with elevation of testicle - suggests epididymitis and not torsion
erythema multiforme
most commonly caused by HSV - target lesions develop over 72 hours - palms, trunk, and mucosal lesions - similar but different from SJS and TEN - tx with steroids
SJS and TEN
SJ is less than 10% (TEN)
HIV is x1000 risk
burn unit, eye consult
SSSS
exotoxin, usually kids <6, pos nikolsky, painful, erythema that is like sandpaper, tx with abx and ICU admit
exfoliative dermatitis
increased cell turnover leading to erythema then scaling tight skin, water and heat loss or regulation leads to 30% mortality
impetigo
honey colored staph and GAS infection on face in kid under 6 or elderly pt. bullous form in toxin and makes bullae/vesicles up to 3cm
erysipselas
raised erythematous plaque acute onset from strep - very SHARP boarder - amoxicillin unless systemic symptoms
nec fasc
clinda stops the toxin formation so it is first line - LIRNEC score
kerion
boggy bald circle - immune response to tinea capitis - tx with antifungal AND steroids
tzanck smear
HSV smear - mostly replaced by culture and PCR
herpetic whitlow
dont confuse with paronychia - its full of dead epithelial cells instead of pus - dont want to spread herpes into deep tissues
scabies tx
5% permethrin on days 1 and 7 of full body. or ivermectin on day 1 and 14 (non preg/breast feeding)
erythema nodosum
cancer, lung infections, IBD, OCPs. mosly young women. NSAIDS and elevation is tx after work up
pemphigus vulgaris
autoimmune loss of keraton adhesion causing plastering and mucous membrane involvement, much like SJS. 40-60yo patients. nikolsky posistive (SJS, TEN, SSSS, PV), not to be confused with bullous pemphigOID that is older than 60 and better prognosis. both tx with steroids
BCC
most common skin cancer
waxy, nodular, wxy, shinny red
resection or chemo
SCC
ulcerating cecnter - resection cures >90%
melanoma
most deadly skin cancer by far, the ABCDE mole of melanoma
animal bits and fight bite that are high risk of infection
leave them open and let antibiotics and washout help
hantavirus
aerosolized rodent feces - pulmonary and fever - can be fatal
rat bite fever
brain and myocardial involvement in febrile illness after a rat bite
black widow
antivenom only for severe symptoms. it comes from horses so risk of anaphylaxis or serum sickness.
otherwise watch or benzos, is an Ach release neurotoxin leading to cramping and spasm
brown recluse
necrotic initially painless wound - no antidote - supportive care
what is serum sickness
immune response delayed by 1 week after antigen exposure
scorpions
antivenom only indicated for bark scorpion and only available in AZ
stinger fish (zebra and lion, urchin)
venom can be inactivated by hot water for 1.5 hours
jelly fish
immerse in vinegar, then remove stingers. box jellyfish has antivenom
tetrodotoxin
blocks Na channels - leads to paralysis
pit vipers
rattle, copperhead, water moccasin(cottonmouth)
cro-fab, elevate
coral snakes
Ach receptor binding - can lead to paralysis, anti-venom, intubation?
malignant hyperthermia - patho and tx
genetic
Ca release from skeletal muscles after succ or inhaled anesthetics
tx with dantrolene
heat stroke
hyperthermia and AMS
usually >40C
hepatic damage
anti-pyretics don’t work
Frostbite
warm water rapid rewarming
leave the blisters in place or needle aspirate
trentch foot
unlike frostbite - this is above freezing temps but for prolonged time, also called immersion foot - this is rewarmed dry
hypothermia cutoffs
30, 32 and 35 C
shivering decreases at every stage mild to severe
core temp during ACLS
needs 32C to be declared dead
only need to shock once until above 32C