WBC Flashcards
M0
Undifferentiated AML
M1
AML without maturation
M2
AML with maturation <–AML with t(8;21) <WHO></WHO>
M3
Acute PromyelocyticLeukemia,
M3m
Microgranular, PromyelocyticLeukemia
M4
Acute Myelomonocytic Leukemia
M5
Acute MonocyticLeukemia
M6
Erythroleukemia(DiGuglielmo’s)
M7
MegakaryoblasticLeukemia
M4Eo
Acute myelomonocyticleukemia with eosinophilia
M5a
Acute monoblasticleukemia, poorly differentiated
M5b
Acute monoblasticleukemia, with differentiation
Neutrophil
pink to tan with violet or lilac
granules
Eosinophil
bright orange refractile granules
Charcoat-Leyden crystals
Found hexagonal bipyramidal crystals are composed of lysophospholipase localized in the cytoplasm of eosinophils
Charcoat-Leyden crystals
Formed when there is an intense or prolonged eosinophilic inflammatory reaction
Thorn Test:
a test to measure adrenocortical function
Basophil
NUCLEUS:Clover-leaf like
CYTOPLASM: purple-black granules that
covers the nucleus
Monocytes
round, oval, kidney shaped horseshoe-shaped, indented or folded with a lacelike or stingy chromatin pattern
CYTOPLASM: blue-gray, with fine azure granules
Lymphocytes
scant basophilic cytoplasm (light sky blue)
Robin’s blue egg cytoplasm
Downey Cells
Any of the several atypical lymphocytes seen in infectious mononucleosis
Downey Cells
Ballerina Skirt Appearance; flared pattern cytoplasm with ends called scalloping which scallops nearby red blood cells
AML
most common type of leukemia in children younger than 18 months of age
Chloroma
Iocalized tumor masses consisting of myeloblasts; Produces a green appearance if the tissue is cut
Auer rods
Also called “faggot cells” which means “bunch of sticks”
AML
Thrombocytopenia
Anemia (normocytic normochromic)
Acute Promyelocytic Leukemia
most aggressive of acute leukemia
AML with t(15;17) in WHO classification
Acute Promyelocytic Leukemia (FAB M3)
Disseminated intravascular coagulation (DIC) is most often associated
Acute Promyelocytic Leukemia (FAB M3)
referred to as Naegelitype monocyticleukemia
Acute Myelomonocytic Leukemia (FAB M4)
AML with inv(16) in WHO classification at risk of leukostasis development
Acute Myelomonocytic Leukemia (FAB M4)
a pathological finding of slightly dilated, thin- walled vessels filled with leukemic cells.
Leukostasis
proliferation of both immature granulocytic
and erythrocytic cell types
Erythemicmyelosisor Di Guglielmo syndrome
most common cancer in children (L1)
Acute Lymphoblastic Leukemia
Terminal deoxynucleotidy ltransferase(TdT)
positive
common ALL antigen (cALLA) is found on the
surface of lymphoblasts in 70% of patients
Acute Lymphoblastic Leukemia