Water soluble vitamins Flashcards
B1
Thiamine
primary function of thiamine
decarboxylation of alpha-keto acids (carbohydrate metabolism)
Deficiency of thiamine
Beriberi (peripheral neuropathy, heart failure)
Wernicke-Korsakoff syndrome
B2
Riboflavin
Primary function of riboflavin
Mitochondrial hydrogen carrier (FMN, FAD)
Deficiency of riboflavin
Angular cheilosis, stomatitis, glossitis
Normocytic anemia
B3
Niacin
Primary function of niacin
Hydrogen acceptor (NAD/NADH)
Deficiency of niacin
Pellagra (dermatitis, dementia, diarrhea)
B6
Pyridoxine
Primary function of pyridoxine
Transamination of AA (amino acid synthesis)
Deficiency of pyridoxine
Cheilosis, stomatitis, glossitis
peripheral neuropathy
B9
folate, folic acid
Primary function of folate, folic acid
Hydroxymethyl/formyl carrier (purine and thymine synthesis)
Deficiency of folate, folic acid
Megaloblastic anemia
Neural tube defects (fetus)