Water Soluble Vitamins Flashcards
B1 (Thiamin) role
Oxidative decarboxylation of a-keto acids &; 2-keto sugars
B1 (Thiamin) deficiency
Beriberi Muscle weakness Anorexia Tachycardia Edema
B1 (Thiamin) sources
Yeast, pork, legumes
B2 (Riboflavin) role
Electron (H) transfer rxns
B2 (Riboflavin) deficiency
Cheilosis
Glossitis
Hyperemia &; edema of pharyngeal &; oral mucus membranes
B2 (Riboflavin) sources
Liver, beef, dairy
B3 (Niacin) role
Electron (H) transfer rxns
B3 (Niacin) deficiency
Pellagra Diarrhea Dermatitis Confusion Dementia
B3 (Niacin) sources
Tuna, liver, poultry, beef, mushrooms
Pantothenic Acid role
Acyl transfer rxns
Pantothenic Acid deficiency
Very rare
Numbness
Tingling of extremities
Fatigue
Pantothenic Acid sources
Widespread, highest in egg yolk, liver, kidney
B6 (Pyridoxine) role
Coenzyme in many transamination &; decarboxylation rxns
B6 (Pyridoxine) deficiency
Dermatitis
Glossitis
Convulsions
B6 (Pyridoxine) sources
Liver, fish, meat
Biotin role
CO2 transfer rxns, carboxylation rxns
Biotin deficiency
Very rare Anorexia Nausea Glossitis Dermatitis
Biotin sources
Yeast, liver, kidney; synthesized by micro-flora
Folic Acid role
1 carbon methyl transfers, AA metabolism
Folic Acid deficiency
Megaloblastic anemia
Fatigue
Depression
Confusion
Folic Acid sources
Brewer’s yeast, liver, green leafy veggies, lima beans
B12 (Cobalamin) role
Methylation of homocysteine to methionine
Conversion of methylmalonyl CoA to succinyl CoA
B12 (Cobalamin) deficiency
Megaloblastic anemia
Degeneration of peripheral nerves
Glossitis
B12 (Cobalamin) sources
Meat, fish, shellfish, poultry, milk
C (Ascorbic Acid) role
Antioxidant, role in collagen synthesis, immune fxn, absorption of non-heme iron
C (Ascorbic Acid) deficiency
Scurvy Fatigue Slow wound healing Bleeding gums Rupture of capillaries
C (Ascorbic Acid) sources
Fruits & veggies
