Water Soluble Vitamins Flashcards

1
Q

B1 (Thiamin) role

A

Oxidative decarboxylation of a-keto acids &; 2-keto sugars

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2
Q

B1 (Thiamin) deficiency

A
Beriberi
Muscle weakness
Anorexia 
Tachycardia
Edema
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3
Q

B1 (Thiamin) sources

A

Yeast, pork, legumes

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4
Q

B2 (Riboflavin) role

A

Electron (H) transfer rxns

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5
Q

B2 (Riboflavin) deficiency

A

Cheilosis
Glossitis
Hyperemia &; edema of pharyngeal &; oral mucus membranes

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6
Q

B2 (Riboflavin) sources

A

Liver, beef, dairy

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7
Q

B3 (Niacin) role

A

Electron (H) transfer rxns

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8
Q

B3 (Niacin) deficiency

A
Pellagra 
Diarrhea 
Dermatitis 
Confusion 
Dementia
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9
Q

B3 (Niacin) sources

A

Tuna, liver, poultry, beef, mushrooms

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10
Q

Pantothenic Acid role

A

Acyl transfer rxns

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11
Q

Pantothenic Acid deficiency

A

Very rare
Numbness
Tingling of extremities
Fatigue

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12
Q

Pantothenic Acid sources

A

Widespread, highest in egg yolk, liver, kidney

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13
Q

B6 (Pyridoxine) role

A

Coenzyme in many transamination &; decarboxylation rxns

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14
Q

B6 (Pyridoxine) deficiency

A

Dermatitis
Glossitis
Convulsions

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15
Q

B6 (Pyridoxine) sources

A

Liver, fish, meat

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16
Q

Biotin role

A

CO2 transfer rxns, carboxylation rxns

17
Q

Biotin deficiency

A
Very rare
Anorexia 
Nausea 
Glossitis 
Dermatitis
18
Q

Biotin sources

A

Yeast, liver, kidney; synthesized by micro-flora

19
Q

Folic Acid role

A

1 carbon methyl transfers, AA metabolism

20
Q

Folic Acid deficiency

A

Megaloblastic anemia
Fatigue
Depression
Confusion

21
Q

Folic Acid sources

A

Brewer’s yeast, liver, green leafy veggies, lima beans

22
Q

B12 (Cobalamin) role

A

Methylation of homocysteine to methionine

Conversion of methylmalonyl CoA to succinyl CoA

23
Q

B12 (Cobalamin) deficiency

A

Megaloblastic anemia
Degeneration of peripheral nerves
Glossitis

24
Q

B12 (Cobalamin) sources

A

Meat, fish, shellfish, poultry, milk

25
Q

C (Ascorbic Acid) role

A

Antioxidant, role in collagen synthesis, immune fxn, absorption of non-heme iron

26
Q

C (Ascorbic Acid) deficiency

A
Scurvy
Fatigue
Slow wound healing
Bleeding gums 
Rupture of capillaries
27
Q

C (Ascorbic Acid) sources

A

Fruits & veggies