Water-Soluble Flashcards
Retinoic Acid fxn
Gene expression
Retinol Fxn
reproduction and growth
Retinal fxn
vision
MC reason for hypovit. A
inadequate intake
1 nut. def. worldwide
vit. A
Other vit. A fxn (3)
glycoprotein synthesis, immune, bone dev., enzymes & growth factors
Hypovit. A symptoms (4)
VISION (night blindness, bitot’s spots, zerophthalmia)
Hyperkeratosis, dec. reproduction, more infxns
Acute hypervit. A symptoms (3)
N/V, Headache/dizzy, double vision
Chronic hyper vit. A symptoms (4)
dry, allopacia, joint/bone fractures, liver damage
Teratongenic affect of vit. A
craniofacial malform.
Sources of preformed vit. A
(retinol/retinol ester; active)
liver, meat, eggs, fortified dairy
Sources of proformed vit. A
(carotinoids)
Stepwise process of carotenoid breakdown (8)
carotenoid > retinal (ox) > retinoic acid > liver > acid reduced > retinol (esterified) > RE > chylomicrons
Stepwise process of vit. A absorption (5)
enterocyte (passive diffusion) > bound to CRBP > esterified via lecithin (LRAT) > RE > Chylomicrons
Vit. A digestion (4)
1) protein removed- Stomach SI (proteases)
2) FA removed- SI (lipases)
»>Free retinol/carotenoid > micelles