water/electrolytes Flashcards

1
Q

what direction does osmosis move water?

A

from low to high concentration of solute (to dilute) or from low to high osmolarity (concentration of solutes)

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2
Q

what do hypertonic and hypotonic mean?

A

hypertonic = higher concentration outside of cell, water will move out and cell becomes flaccid
hypotonic = higher concentration inside of cell, water moves in and cell becomes turgid

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3
Q

what are osmoconformers and what do they do?

A
  • sharks, rays etc
  • matches their electrolyte concentration to its aquatic surroundings (no need for regulation)
  • blood has low ion concentration and high urea (makes it isosmotic)
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4
Q

what osmotic stress do salt water fish experience and how do they resolve it?

A
  • seawater concentration > internal concentration (hyperosmotic)
  • water tends to move out
  • resolves by drinking water to replace loss, but gains excess of electrolytes
  • electrolytes are actively pumped back into surroundings
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5
Q

what osmotic stress do fresh water fish experience and how do they resolve it?

A
  • water concentration < internal concentration (hyposmotic)
  • water tends to move in
  • must get rid of excess water through urine
  • electrolytes diffuse through gills
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6
Q

how do terrestrial animals lose water and how do they resolve this?

A
  • loses water through evaporation
  • drinks water + eats for electrolytes
  • gets rid of excess through urine
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7
Q

how do different types of animals get rid of ammonia/nitrogenous waste?

A

freshwater fish: diluted and excreted through urine
bony fish: diffuses through gills
mammals: converted into less toxic urea and extreted through urine (high water cost but low energy)
birds/reptiles: converted into uric acid and excreted as a paste (low water cost but high energy
sharks: actively secretes salts out rectal gland (Na/K pumps)

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8
Q

what are the steps for salt excretion?

A

1) Na-K pump pushes Na out of epithelial cells into interstitial fluid
2) Na, K and Cl enter cell following Na gradient
3) Cl channels let Cl ions out through lumen into environment
4) Na channels allow Na to exit into lumen

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9
Q

what organs are involved in nitrogenous waste disposal?

A
  • kidneys (produces urine)
  • ureter (transports urine)
  • bladder (stores urine)
  • urethra (excretes urine)
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10
Q

what are the five parts of a nephron?

A

1) renal corpuscle
2) proximal tubule
3) loops of henle
4) distal tubule
5) collecting duct

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11
Q

what happens during urine filtration? what part of the nephron?

A
  • renal corpuscle (glomerulus + bowmans capsule)
  • small molecules go through filtration pores to be absorbed
  • large molecules stay in blood and continue through nephrons
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12
Q

what is GFR?

A
  • glomerular filtration rate
  • rate at which filtration occurs in the glomerulus
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13
Q

what happens in the proximal tubule?

A
  • selective reabsorption of salts (active) and water (osmosis)
  • Na-K pump moves Na in
  • Na activates cotransporters that move solutes from filtrate into blood, water follows
  • most of reabsorption here
  • high SA from microvili
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14
Q

what happens in the loops of henle?

A

descending loop:
- salty surroundings cause passive transport of water out
thin ascending loop:
- passive transport of Na and Cl
thick ascending loop:
- active transport of Na and Cl

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15
Q

what is the myogenic response for GFR?

A
  • blood enters from afferent arteriole
  • if blood pressure increases, smooth muscle cells contract to control blood flow
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16
Q

what is the tubuloglomerular response for GFR?

A
  • macula cells sense changes in distal tubules
  • regulates flow by signalling to smooth muscle to contract/relax
17
Q

what is the mesangial response for GFR?

A
  • slits change diameter of openings to control permeability of GFR
18
Q

what happens in the distal tubule?

A
  • fine tunes reabsorption and maintains homeostasis
  • if dehydrated, releases ADH which increases urea permeability and adds aquaporins (higher water permeability), produces less urine
  • if low on salt, releases aldosterone which activates more Na pumps (more Na absorbed) and secretes K/Cl
19
Q

what is the energy cost of ammonia, urea and uric acid?

A

ammonia = low
urine = high
uric acid = high

20
Q

what is the toxicity of ammonia, urea and uric acid?

A

ammonia = high
urine = medium
uric acid = low